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William B Nicolson
Researcher at University of Leicester
Publications - 20
Citations - 180
William B Nicolson is an academic researcher from University of Leicester. The author has contributed to research in topics: Sudden cardiac death & Medicine. The author has an hindex of 6, co-authored 14 publications receiving 152 citations. Previous affiliations of William B Nicolson include National Institute for Health Research & Glenfield Hospital.
Papers
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Journal ArticleDOI
New approach for T-wave peak detection and T-wave end location in 12-lead paced ECG signals based on a mathematical model
João Paulo do Vale Madeiro,João Paulo do Vale Madeiro,William B Nicolson,Paulo César Cortez,Joao Alexandre Lobo Marques,Carlos Román Vázquez-Seisdedos,Narmadha Elangovan,G. André Ng,Fernando S. Schlindwein +8 more
TL;DR: An innovative approach for T-wave peak detection and subsequent T- wave end location in 12-lead paced ECG signals based on a mathematical model of a skewed Gaussian function is presented.
Journal ArticleDOI
A novel surface electrocardiogram-based marker of ventricular arrhythmia risk in patients with ischemic cardiomyopathy.
William B Nicolson,William B Nicolson,Gerry P McCann,Gerry P McCann,Peter D. Brown,A.J. Sandilands,Peter J. Stafford,Fernando S. Schlindwein,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,G. André Ng,G. André Ng,G. André Ng +13 more
TL;DR: A novel VA risk marker, R2I2, is developed and test and shown that it correlated with a structural measure of arrhythmic risk and predicted risk of VA or death in patients with ICM, and may improve risk stratification and merits further evaluation.
Journal ArticleDOI
Prospective evaluation of two novel ECG-based restitution biomarkers for prediction of sudden cardiac death risk in ischaemic cardiomyopathy
William B Nicolson,William B Nicolson,William B Nicolson,Gerry P McCann,Gerry P McCann,Gerry P McCann,M.I. Smith,A.J. Sandilands,Peter J. Stafford,Fernando S. Schlindwein,Fernando S. Schlindwein,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,G. André Ng,G. André Ng,G. André Ng +16 more
TL;DR: R2I2 and PERS each independently and in combination, identify patients with ICM that are at high risk of developing ventricular arrhythmias (VA) and represent promising risk markers for SCD discrimination.
Journal ArticleDOI
Regional fractionation and dominant frequency in persistent atrial fibrillation: effects of left atrial ablation and evidence of spatial relationship.
Jiun Tuan,Mohamed Jeilan,Suman Kundu,William B Nicolson,William B Nicolson,Chung I,Peter J. Stafford,G.A. Ng,G.A. Ng +8 more
TL;DR: Complex fractionated electrograms-mean and DF appear to share only modest spatial correlation and are affected to different extents by ablation, suggesting that they are either separate entities or reflect different components of the same substrate.
Patent
Method and apparatus for evaluating cardiac function
William B Nicolson,Andre G. Ng +1 more
TL;DR: In this article, a method for assessing the electrical function of a heart, comprising the steps of determining a value derived from the output of that lead and which corresponds to an action potential duration, and assessing the differences between the determined relationships for each of the plurality of leads.