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William J. Cunliffe
Researcher at University of Leeds
Publications - 285
Citations - 15842
William J. Cunliffe is an academic researcher from University of Leeds. The author has contributed to research in topics: Acne & Isotretinoin. The author has an hindex of 66, co-authored 285 publications receiving 15234 citations. Previous affiliations of William J. Cunliffe include Leeds General Infirmary & University of Nottingham.
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Journal ArticleDOI
Management of Acne: A Report From a Global Alliance to Improve Outcomes in Acne
Harald Gollnick,William J. Cunliffe,Diane Berson,Brigitte Dreno,Andrew Yule Finlay,James J. Leyden,Alan R. Shalita,Diane Thiboutot +7 more
TL;DR: The Global Alliance to Improve Outcomes in Acne as mentioned in this paper has developed consensus recommendations for the treatment of acne, which are evidence-based when possible, and which include input from numerous countries The members of the group represent a broad list of international dermatologists with a special interest in acne and reflect a wide range of experiences and opinions.
Journal ArticleDOI
Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses
Jenny Kim,Maria Teresa Ochoa,Stephan R. Krutzik,Osamu Takeuchi,Satoshi Uematsu,Annaliza J. Legaspi,Hans Brightbill,Diana B. Holland,William J. Cunliffe,Shizuo Akira,Peter A. Sieling,Paul J. Godowski,Robert L. Modlin +12 more
TL;DR: Data suggest that P. acnes triggers inflammatory cytokine responses in acne by activation of TLR2, which may provide a novel target for treatment of this common skin disease.
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A clinical evaluation of acne scarring and its incidence.
TL;DR: Results indicate that facial scarring affects both sexes equally and occurs to some degree in 95% of cases, and emphasizes the need for earlier adequate therapy in an attempt to minimize the subsequent scarring caused by acne.
Journal ArticleDOI
Inflammatory events are involved in acne lesion initiation.
Anthony H.T. Jeremy,Diana B. Holland,Susan G. Roberts,Kathryn F. Thomson,William J. Cunliffe +4 more
TL;DR: Novel evidence is provided for vascular endothelial cell activation and involvement of inflammatory responses in the very earliest stages of acne lesion development.
Journal ArticleDOI
Pathogenesis of acne
William J. Cunliffe,Sam Shuster +1 more
TL;DR: This work concludes that acne vulgaris lesions develop when (supposedly largely androgen-mediated) increased sebum production, ductal hypercornification, and propionibacteria come together with local inflammatory process in the unlucky affected individual.