W
Wojciech T. Markiewicz
Researcher at Polish Academy of Sciences
Publications - 83
Citations - 1089
Wojciech T. Markiewicz is an academic researcher from Polish Academy of Sciences. The author has contributed to research in topics: Oligonucleotide & DNA. The author has an hindex of 20, co-authored 82 publications receiving 1043 citations.
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Journal ArticleDOI
DNA sequencing with positive and negative errors.
TL;DR: An algorithm is proposed that solves a computational phase of this approach in the presence of both positive and negative errors resulting from the hybridization experiment, and behaves surprisingly well if only positive errors appear.
Journal ArticleDOI
Tabu search for DNA sequencing with false negatives and false positives
Jacek Blazewicz,Jacek Blazewicz,Piotr Formanowicz,Piotr Formanowicz,Marta Kasprzak,Marta Kasprzak,Wojciech T. Markiewicz,J. Wȩglarz,J. Wȩglarz +8 more
TL;DR: In the paper, a heuristic algorithm based on tabu search is proposed that has low complexity and high accuracy for both types of errors: false negatives and false positives.
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Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichloroethyl group and 31P NMR as a new tool for analysis of deblocking of internucleotide phosphate protecting groups.
Ryszard W. Adamiak,Ewa Biala,Grześkowiak,Ryszard Kierzek,Adam Kraszewski,Wojciech T. Markiewicz,Jacek Stawinski,Wiewiórowski +7 more
TL;DR: 31P NMR spectroscopy has been proposed as a new tool for analysis of removal of internucleotide phosphate protecting groups-a crucial step in oligonucleotides synthesis via phosphotriester approach.
Journal ArticleDOI
Multivalent display system on filamentous bacteriophage pVII minor coat protein
TL;DR: In this article, the authors describe genetically stable fusion of scFv fragments to gene VII directly in the phage genome, thus giving rise to a multivalent display system where infectivity is not comprised.
Journal ArticleDOI
The chemical synthesis of the anticodon loop of an eukaryotic initiator tRNA containing the hypermodified nucleoside N6-/N-threonylcarbonyl/-adenosine/t6A/1
Ryszard W. Adamiak,Ewa Biala,K. Grześkowiak,Ryszard Kierzek,Adam Kraszewski,Wojciech T. Markiewicz,J. Okupniak,Jacek Stawinski,M. Wiewiórowski +8 more
TL;DR: The first example of chemical synthesis of oligoribonucleotide containing the hypermodified nucleoside N6-/N-threonylcarbonyl/-adenosine /t6A/ is presented, which is related to the anticodon loop of the initiator tRNA from yellow lupine.