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Wolfgang Oppolzer
Researcher at University of Geneva
Publications - 326
Citations - 11570
Wolfgang Oppolzer is an academic researcher from University of Geneva. The author has contributed to research in topics: Intramolecular force & Enantioselective synthesis. The author has an hindex of 61, co-authored 326 publications receiving 11387 citations. Previous affiliations of Wolfgang Oppolzer include University of Waterloo & Harvard University.
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Optically Pure, Crystalline ′Acetate′‐Aldols from N‐Acetylbornane‐10,2‐ sultam.
TL;DR: O -Silylation of N -acetylsultam 2 gives O -silyl- N, O -ketene acetal 3 which undergoes TiCl 4 promoted addition to aromatic and aliphatic aldehydes to afford, after flash chromatography, diastereomerically pure, crystalline aldols 5 which are readily converted to enanti-hydroxy carboxylic acids or esters as discussed by the authors.
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Asymmetric Induction on Copper(I) Chloride Catalyzed 1,4‐Addition of Alkylmagnesium Chlorides to α,β‐Disubstituted (E)‐Enoylsultams and Subsequent Protonation.
Wolfgang Oppolzer,A. J. Kingma +1 more
TL;DR: In this article, conjugated N-enoylsultams with alkyl Grignard reagents/CuCl and aq. NH4Cl solution generated selectively two stereogenic centers at C(α) and C(β) providing, after flash chromatography and crystallization, acylsultams 5 in high purity.
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Palladium-Catalyzed Cyclizations of Enantiomerically Pure Acyclic 4- Acetoxy-2,8-nonadines: Efficient Chirality Transfer.
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An enantioselective total synthesis of natural (+)‐luciduline
TL;DR: In this article, the naturally occurring Lycopodium alkaloid (+)-luciduline (1) has been synthesized from (R)-5-methyl-cyclohex-2-en-1-one (12) by a sequence of seven steps (s. Scheme 6) in 33% overall yield.