The invention relates to a protein aryl derivative and a preparation method and application thereof The protein aryl derivative is prepared by taking protein as a raw material, carrying out a coupling reaction with an aryl compound in the presence of an oxidant, a copper catalyst and a surfactant, and carrying out a diaryl coupling reaction The protein aryl derivative provided by the invention has the advantages that the preparation method is simple, efficient and convenient; and compared with the original protein, the activity of the arylated protein is greatly improved

Protein aryl derivative and preparation method thereof

The invention relates to a 5-aryl-2-arylselenenyl-1,3-oxazole compound and a preparation method. The preparation method comprises the following step: in an organic solvent, by taking 5-aryl-1,3-oxazole and aromatic iodide as raw materials and single selenium as a seleno-based reagent, and under the coactions of a copper catalyst and an alkali, carrying out a serial reaction, thereby obtaining the5-aryl-2-arylselenenyl-1,3-oxazole compound. The method is simple in reaction condition, high in product yield and purity, develops novel synthesis routes and methods for the 5-aryl-2-arylselenenyl-1,3-oxazole compound, and has good application potential and study values.

Wu Ge

Papers

5-aryl-2-arylselenenyl-1,3-oxazole compound and preparation method