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Xian Zhang
Researcher at Jiangnan University
Publications - 143
Citations - 2085
Xian Zhang is an academic researcher from Jiangnan University. The author has contributed to research in topics: Chemistry & Fermentation. The author has an hindex of 24, co-authored 101 publications receiving 1479 citations.
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Journal ArticleDOI
The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis.
Xian Zhang,Rongzhen Zhang,Teng Bao,Zhiming Rao,Yang Taowei,Meijuan Xu,Zhenghong Xu,Huazhong Li,Shang-Tian Yang +8 more
TL;DR: Through metabolic engineering strategies, acetoin production was improved, and the production of 2,3-butanediol, lactic acid and ethanol were decreased, while the fermentation duration was decreased 1.7-fold.
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Production of 2,3‐butanediol from glucose by GRAS microorganism Bacillus amyloliquefaciens
TL;DR: The strain B10‐127 produced 2,3‐BD effectively under the condition of 20% glucose (quality concentration), showed a high‐glucose tolerance and showed an excellent candidate for the microbial fermentation of 2, 3‐BD on an industrial scale.
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Metabolic engineering strategies for acetoin and 2,3-butanediol production: advances and prospects.
TL;DR: This review summarizes metabolic engineering strategies for improvement of microbial acetoin and 2,3-BD production and proposes enhancements to current acetoin-2,3,BD production strategies, by offering a metabolic engineering approach that is guided by systems biology and synthetic biology.
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Improved production of 2,3-butanediol in Bacillus amyloliquefaciens by over-expression of glyceraldehyde-3-phosphate dehydrogenase and 2,3-butanediol dehydrogenase.
TL;DR: Co-overexpression of bdh and gapA genes proved an effective method for enhancing 2,3-BD production and inhibiting the accumulation of unwanted by-products (acetoin, lactate and succinate).
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High-level production of melanin by a novel isolate of Streptomyces kathirae.
TL;DR: To enhance melanin production, the culture medium was optimized by conducting a series of batch fermentations in a defined medium, and the results were analysed statistically using a response surface method to provide novel data on melanin fermentation and identify an excellent candidate for industrial-scale microbial fermentation of melanin.