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Xianhuan Shen
Publications - 3
Citations - 91
Xianhuan Shen is an academic researcher. The author has contributed to research in topics: Genotype & Valproic Acid. The author has an hindex of 1, co-authored 1 publications receiving 21 citations.
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Journal ArticleDOI
Computational Approaches in Preclinical Studies on Drug Discovery and Development.
Fengxu Wu,Yuquan Zhou,Langhui Li,Xianhuan Shen,Ganying Chen,Xiaoqing Wang,Xianyang Liang,Mengyuan Tan,Zunnan Huang +8 more
TL;DR: A systematic classification and description of the databases and software commonly used for ADMET prediction and some applications that are related to the prediction categories and web tools are listed.
Journal ArticleDOI
Pharmacogenetics-based population pharmacokinetic analysis and dose optimization of valproic acid in Chinese southern children with epilepsy: Effect of ABCB1 gene polymorphism
Xianhuan Shen,Xinyi Chen,Jieluan Lu,Qing Chen,Wenzhou Li,Jiahao Zhu,Yaodong He,Huijuan Guo,Chenshu Xu,Xiaomei Fan +9 more
TL;DR: Wang et al. as mentioned in this paper established a population pharmacokinetic (PPK) model of valproic acid (VPA) in pediatric patients with epilepsy in southern China, and provided guidance for individualized medication of VPA therapy.
Journal ArticleDOI
SCN1A Polymorphisms and Haplotypes Are Associated With Valproic Acid Treatment Outcomes in Chinese Children With Epilepsy.
Jiahao Zhu,Jieluan Lu,Xianhuan Shen,Yaodong He,Han-Bing Xia,Wenzhou Li,Huijuan Guo,Jianping Zhang,Xiaomei Fan +8 more
TL;DR: Wang et al. as discussed by the authors explored the association of SCN1A polymorphisms with efficacy and adverse drug reactions (ADRs) related to valproic acid (VPA) among Chinese children with epilepsy.