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Xiao-Le Han
Researcher at South Central University for Nationalities
Publications - 21
Citations - 905
Xiao-Le Han is an academic researcher from South Central University for Nationalities. The author has contributed to research in topics: Quenching (fluorescence) & Chemistry. The author has an hindex of 10, co-authored 16 publications receiving 725 citations. Previous affiliations of Xiao-Le Han include Wuhan University of Science and Technology & Wuhan University.
Papers
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Journal ArticleDOI
Synthesis of a novel hydrazone derivative and biophysical studies of its interactions with bovine serum albumin by spectroscopic, electrochemical, and molecular docking methods
Fang-Fang Tian,Feng-Lei Jiang,Xiao-Le Han,Chen Xiang,Yu-Shu Ge,Jia-Han Li,Yue Zhang,Ran Li,Xin-Liang Ding,Yi Liu +9 more
TL;DR: It is shown that DBH can efficiently bind with BSA and be transported to the focuses needed and is supported by a docking study using a BSA crystal model.
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Spectroscopic, structural and thermodynamic properties of chlorpyrifos bound to serum albumin: A comparative study between BSA and HSA.
Xiao-Le Han,Fang-Fang Tian,Yu-Shu Ge,Feng-Lei Jiang,Lu Lai,Dong-Wei Li,Qiuliyang Yu,Jia Wang,Chen Lin,Yi Liu +9 more
TL;DR: The fluorescence spectra revealed that CPF causes the quenching of the fluorescence emission of serum albumin, and the alterations of protein secondary structure in the presence of CPF were confirmed by the evidences from UV and CD spectra.
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Binding interaction of quinclorac with bovine serum albumin: a biophysical study.
TL;DR: It was proved that the probable quenching mechanism of BSA by quinclorac was dynamic quenched and the alterations of protein secondary structure in the presence of QUC were confirmed by the evidences from three-dimensional fluorescence, synchronous fluorescence and CD spectroscopy.
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Spectroscopic studies on the interactions between CdTe quantum dots coated with different ligands and human serum albumin
Lu Lai,Chen Lin,Zi-Qiang Xu,Xiao-Le Han,Fang-Fang Tian,Ping Mei,Dong-Wei Li,Yu-Shu Ge,Feng-Lei Jiang,Ye-Zhong Zhang,Yi Liu,Yi Liu +11 more
TL;DR: The results demonstrate that the interaction mechanism between the positively charged QDs (CA-CdTe) and HSA is significantly different from negatively charged QD, and it was proven that QDs can induce the conformational changes of HSA from the CD spectra and the three-dimensional fluorescence spectra.
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The adsorption of an anticancer hydrazone by protein: an unusual static quenching mechanism
TL;DR: In this article, a novel hydrazone, 4-chloro-N′-(pyridin-2-ylmethylene)benzohydrazide (CPBH), has been synthesized through a one-pot synthesis method and used as a chemical probe to find the structural cause of the unusual static quenching mechanism in the interaction with serum albumin.