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Xiao Sun
Researcher at The Chinese University of Hong Kong
Publications - 8
Citations - 231
Xiao Sun is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Oocyte & Zebrafish. The author has an hindex of 4, co-authored 6 publications receiving 98 citations.
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Journal ArticleDOI
IGFs mediate the action of LH on oocyte maturation in zebrafish.
TL;DR: The results clearly demonstrated that IGFs, particularly the gonad-specific IGF-3, act as important mediators of LH action on oocyte maturation in zebrafish.
Journal ArticleDOI
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1
Xiao Sun,Yingzhi Liu,Ziheng Huang,Wenye Xu,Wei Hu,Lina Yin,Zhe Liu,Hung Chan,Ju deng Zeng,Xiaodong Liu,Huarong Chen,Jun Yu,Francis K.L. Chan,Siew C. Ng,Sunny H. Wong,Maggie Haitian Wang,Tony Gin,Gavin M. Joynt,David S.C. Hui,Xuan Zou,Yuelong Shu,Christopher H.K. Cheng,Shisong Fang,Huanle Luo,Jing Lu,Matthew Chan,Li Zhang,William K.K. Wu +27 more
TL;DR: In this article , the inflammasome-related NOD-like receptor signaling was activated in SARS-CoV-2-infected lung epithelial cells and Coronavirus Disease 2019 (COVID-19) patients' lung tissues.
Journal ArticleDOI
Bufalin, a Traditional Chinese Medicine Compound, Prevents Tumor Formation in Two Murine Models of Colorectal Cancer
Xiao Sun,Tony T.H. Ng,Kathy W.Y. Sham,Lin Zhang,Matthew T. V. Chan,William K.K. Wu,Christopher H.K. Cheng +6 more
TL;DR: The results revealed that long-term administration of low-dose bufalin effectively suppressed tumorigenesis in both colorectal cancer models, accompanied by attenuated epithelial cell proliferation and inhibited oncogenic NF-κB and PI3K/Akt pathways.
Journal ArticleDOI
Lysosome activation in peripheral blood mononuclear cells and prognostic significance of circulating LC3B in COVID-19.
Shisong Fang,Lin Zhang,Yingzhi Liu,Wenye Xu,Weihua Wu,Ziheng Huang,Xin Wang,Hui Liu,Ying Sun,Renli Zhang,Bo Peng,Xiaodong Liu,Xiao Sun,Jun Yu,Francis K.L. Chan,Siew C. Ng,Sunny H. Wong,Maggie Haitian Wang,Tony Gin,Gavin M. Joynt,David S.C. Hui,Tiejian Feng,William K.K. Wu,Matthew T. V. Chan,Xuan Zou,Junjie Xia +25 more
TL;DR: In this article, the authors performed transcriptome analysis of peripheral blood mononuclear cells (PBMCs) from COVID-19 patients and identified the aberrant upregulation of genes in the lysosome pathway.
Journal ArticleDOI
Igf3 is essential for ovary differentiation in zebrafish
TL;DR: It is demonstrated that Igf3 is essential for ovary differentiation in zebrafish through regulating cell proliferation and interacting with estrogen.