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Xuan Zou
Researcher at Centers for Disease Control and Prevention
Publications - 33
Citations - 2494
Xuan Zou is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 8, co-authored 21 publications receiving 1787 citations.
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Journal ArticleDOI
Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study.
Qifang Bi,Yongsheng Wu,Shujiang Mei,Chenfei Ye,Xuan Zou,Zhen Zhang,Xiaojian Liu,Lan Wei,Shaun A. Truelove,Tong Zhang,Wei Gao,Cong Cheng,Xiujuan Tang,Xiaoliang Wu,Yu Wu,Binbin Sun,Suli Huang,Yu Sun,Juncen Zhang,Ting Ma,Justin Lessler,Tiejian Feng +21 more
TL;DR: An analysis of data from the Shenzhen Center for Disease Control and Prevention identified 391 SARS-CoV-2 cases and 1286 close contacts shows that isolation and contact tracing reduce the time during which cases are infectious in the community, thereby reducing the R.
Posted ContentDOI
Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts
Qifang Bi,Yongsheng Wu,Shujiang Mei,Chenfei Ye,Xuan Zou,Zhen Zhang,Xiaojian Liu,Lan Wei,Shaun A. Truelove,Tong Zhang,Wei Gao,Cong Cheng,Xiujuan Tang,Xiaoliang Wu,Yu Wu,Binbin Sun,Suli Huang,Yu Sun,Juncen Zhang,Ting Ma,Justin Lessler,Teijian Feng +21 more
TL;DR: This work shows that heightened surveillance and isolation, particularly contact tracing, reduces the time cases are infectious in the community, thereby reducing R.CoV-2's overall impact, however, its overall impact is uncertain and highly dependent on the number of asymptomatic cases.
Journal ArticleDOI
SARS-CoV-2 and Three Related Coronaviruses Utilize Multiple ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig.
Yujun Li,Haimin Wang,Xiaojuan Tang,Shisong Fang,Danting Ma,Chengzhi Du,Yifei Wang,Hong Pan,Weitong Yao,Renli Zhang,Xuan Zou,Jie Zheng,Liangde Xu,Michael Farzan,Guocai Zhong +14 more
TL;DR: Improved ACE2-Ig variants developed in this study could potentially be developed to protect from Sars-CoV-2 and some other SARS-like viruses that might spillover into humans in the future.
Journal ArticleDOI
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1
Xiao Sun,Yingzhi Liu,Ziheng Huang,Wenye Xu,Wei Hu,Lina Yin,Zhe Liu,Hung Chan,Ju deng Zeng,Xiaodong Liu,Huarong Chen,Jun Yu,Francis K.L. Chan,Siew C. Ng,Sunny H. Wong,Maggie Haitian Wang,Tony Gin,Gavin M. Joynt,David S.C. Hui,Xuan Zou,Yuelong Shu,Christopher H.K. Cheng,Shisong Fang,Huanle Luo,Jing Lu,Matthew Chan,Li Zhang,William K.K. Wu +27 more
TL;DR: In this article , the inflammasome-related NOD-like receptor signaling was activated in SARS-CoV-2-infected lung epithelial cells and Coronavirus Disease 2019 (COVID-19) patients' lung tissues.
Journal ArticleDOI
Insight into the practical performance of RT-PCR testing for SARS-CoV-2 using serological data: a cohort study.
Zhen Zhang,Qifang Bi,Shisong Fang,Lan Wei,Xin Wang,Jianfan He,Yongsheng Wu,Xiaojian Liu,Wei Gao,Renli Zhang,Wenfeng Gong,Qiru Su,Andrew S. Azman,Justin Lessler,Xuan Zou +14 more
TL;DR: In this article, the authors evaluated the performance of RT-PCR-based surveillance protocols and determined the extent of undetected SARS-CoV-2 infection in Shenzhen, China.