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Xiaohua Wang
Researcher at Nanjing Medical University
Publications - 7
Citations - 268
Xiaohua Wang is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Triple-negative breast cancer & Cell migration. The author has an hindex of 5, co-authored 7 publications receiving 161 citations.
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Journal ArticleDOI
Tumor-associated macrophages correlate with phenomenon of epithelial-mesenchymal transition and contribute to poor prognosis in triple-negative breast cancer patients.
Weijie Zhang,Xiaohua Wang,Shao-ting Gao,Cheng Chen,Xin-Yun Xu,Qi Sun,Zhi-Hua Zhou,Guozhong Wu,Qiao Yu,Guifang Xu,Yong-Zhong Yao,Wenxian Guan,Wenxian Guan +12 more
TL;DR: High infiltration of TAMs was associated with low expression of E-cadherin and could be used as an unfavorable prognostic factor for patients with TNBC and Multivariate analysis indicated that infiltrating TAMs and low expression in TNBC patients were independent prognostic factors of overall survival and disease-free survival in T NBC patients.
Journal ArticleDOI
miR-613 inhibits cell migration and invasion by downregulating Daam1 in triple-negative breast cancer.
Huaping Xiong,Ting Yan,Weijie Zhang,Fangfang Shi,Xuesong Jiang,Xiaohua Wang,Shoushan Li,Ying Chen,Cheng Chen,Yichao Zhu +9 more
TL;DR: MiR-613 weakens the resistance of TNBC cells against paclitaxel rather than adriamycin, cyclophosphamide, docetaxel, and kaempferol and is involved in cell migration and invasion of T NBC cells via targeting Daam1/RhoA signaling pathway.
Journal ArticleDOI
Cancer-Associated Fibroblasts Correlate with Tumor-Associated Macrophages Infiltration and Lymphatic Metastasis in Triple Negative Breast Cancer Patients.
Jing Zhou,Xiaohua Wang,Yi-Xin Zhao,Cheng Chen,Xin-Yun Xu,Qi Sun,Hongyan Wu,Ming Chen,Jianfeng Sang,Lei Su,Xiaoqiao Tang,Xianbiao Shi,Yin Zhang,Qiao Yu,Yongzhong Yao,Yongzhong Yao,Weijie Zhang +16 more
TL;DR: Cancer-associated fibroblasts were associated with infiltration of CD163-positive macrophages and lymphatic metastasis, and may be potential prognostic predictors of TNBC.
Journal ArticleDOI
Low dose of kaempferol suppresses the migration and invasion of triple-negative breast cancer cells by downregulating the activities of RhoA and Rac1
Shoushan Li,Ting Yan,Rong Deng,Xuesong Jiang,Huaping Xiong,Yuan Wang,Qiao Yu,Xiaohua Wang,Cheng Chen,Yichao Zhu +9 more
TL;DR: The low dose of kaempferol inhibits the migration and invasion of TNBC cells via blocking RhoA and Rac1 signaling pathway.
Journal ArticleDOI
The clinical and prognostic significance of paraoxonase-2 in gastric cancer patients: immunohistochemical analysis.
Xiaohua Wang,Guifang Xu,Jingyuan Zhang,Shuaiyu Wang,Min Ji,Lei Mo,Mengxia Zhu,Jun Li,Guoren Zhou,Lu Jianwei,Cheng Chen +10 more
TL;DR: Findings give first evidence that PON2 serves as oncogene in GC, and in vitro studies indicated that silencing of Pon2 expression inhibited GC cell proliferation, migration and invasion.