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Xiaoqin Tong
Researcher at University of Kansas
Publications - 4
Citations - 178
Xiaoqin Tong is an academic researcher from University of Kansas. The author has contributed to research in topics: Withanolide & Withaferin A. The author has an hindex of 4, co-authored 4 publications receiving 158 citations.
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Journal ArticleDOI
Withaferin A, a Cytotoxic Steroid from Vassobia breviflora, Induces Apoptosis in Human Head and Neck Squamous Cell Carcinoma
TL;DR: This investigation constitutes the first report of the antiproliferative activity of withaferin A (1) against head and neck squamous carcinoma.
Journal ArticleDOI
Cytotoxic withanolide constituents of Physalis longifolia.
Huaping Zhang,Abbas Samadi,Robert J. Gallagher,Juan J. Araya,Xiaoqin Tong,Victor W. Day,Mark S. Cohen,Kelly Kindscher,Rao Gollapudi,Barbara N. Timmermann +9 more
TL;DR: Using a MTS viability assay, eight withanolides and four acetylated derivatives showed potent cytotoxicity against human head and neck squamous cell carcinoma, melanoma, and normal fetal fibroblast cells with IC₅₀ values in the range between 0.067 and 9.3 μM.
Journal ArticleDOI
Chlorinated Withanolides from Withania somnifera.
TL;DR: All structures were elucidated on the basis of spectroscopic methods (IR, HRESIMS, 1D/2D NMR) and X-ray crystallography confirmed the absolute configuration of 1.5-methoxy-2,3-dihydrowithaferin A.
Journal ArticleDOI
6α,7α-Epoxy-5α-hydroxy-1-oxo-22R-witha-2,24-dienolide(withanolide B), 5β,6β-Epoxy-4β,20-dihydroxy-1-oxo-22R-witha-2,24-dienolide(withanolide D), and 4β,27-Dihydroxy-1-oxo-22R-witha-2,5,24-trienolide(5,6-deoxywithaferin A) in Roots of Withania somnifera: Isolation and Their Crystal Structures
TL;DR: In this paper, the structures of these withanolides were established by spectroscopic analysis and X-ray diffraction studies as withanolide B, with-anolide D, and 5,6-deoxywithaferin A, respectively.