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Xiaozhou Mou
Researcher at Zhejiang University
Publications - 37
Citations - 670
Xiaozhou Mou is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 13, co-authored 18 publications receiving 479 citations. Previous affiliations of Xiaozhou Mou include Zhejiang California International NanoSystems Institute.
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Journal ArticleDOI
Human Menstrual Blood-Derived Stem Cells Ameliorate Liver Fibrosis in Mice by Targeting Hepatic Stellate Cells via Paracrine Mediators
Lijun Chen,Chun-feng Zhang,Lu Chen,Xiaojun Wang,Bingyu Xiang,Xiaoxing Wu,Yang Guo,Xiaozhou Mou,Li Yuan,Bo Chen,Jinfu Wang,Charlie Xiang +11 more
TL;DR: Investigating the therapeutic effects of MenSC transplantation in a carbon tetrachloride‐induced mouse model of liver fibrosis revealed that MenSCs markedly improved liver function, attenuated collagen deposition, and inhibited activated hepatic stellate cells up to 2 weeks after transplantation.
Journal ArticleDOI
Menstrual blood-derived mesenchymal stem cells differentiate into functional hepatocyte-like cells.
Xiaozhou Mou,Jian Lin,Jinyang Chen,Yifei Li,Xiaoxing Wu,Bingyu Xiang,Cai-yun Li,Ju-ming Ma,Charlie Xiang +8 more
TL;DR: MenSCs may serve as an ideal, easily accessible source of material for tissue engineering and cell therapy of liver tissues and it was shown that MenSC-derived HLC transplantation could restore the serum ALB level and significantly suppressed transaminase activity of liver injury animals.
Journal ArticleDOI
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis
Xue Zhang,Yun Zhang,Bo Tao,Li Teng,Yanwei Li,Rui Cao,Qiu Gui,Madong Ye,Xiaozhou Mou,Hongqiang Cheng,Hu Hu,Ren Zhou,Ximei Wu,Qiang-min Xie,Wen Ning,Maode Lai,Huahao Shen,Gen-Sheng Feng,Yuehai Ke +18 more
TL;DR: A novel role of tyrosine phosphatase Shp2 in surfactant homeostasis is identified, and deregulation of Shp1 triggers spontaneous pulmonary fibrosis with minimal inflammation.
Journal ArticleDOI
A dynamic real-time method for monitoring epithelial barrier function in vitro.
Mingjiao Sun,Huiying Fu,Hongqiang Cheng,Qian Cao,Yuan Zhao,Xiaozhou Mou,Xue Zhang,Xiuhua Liu,Yuehai Ke +8 more
TL;DR: This work introduces an electronic impedance-based analysis using a real-time xCELLigence system to record the dynamic processes of ethanol-induced intestinal barrier dysfunction and identifies the in vitro roles of the inducible nitric oxide synthase inhibitor, epithelial growth factor, tyrosine kinases, and phosphatases in regulating epithelial barrier function in response to ethanol administration.
Journal ArticleDOI
Prevalence of JC virus in Chinese patients with colorectal cancer.
Xiaozhou Mou,Ling Chen,Fanlong Liu,Jian Lin,Pingping Diao,Haohao Wang,Yifei Li,Jianjiang Lin,Lisong Teng,Charlie Xiang,Charlie Xiang +10 more
TL;DR: JCV infection is frequently present in colorectal tumor tissues of CRC patients and the JCV prevalence in PB samples was significantly associated with the J CV status in tissue samples, whether PB JCV detection can serve as a marker for JCV status of CRC requires further study.