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Xiaozhou Mou

Researcher at Zhejiang University

Publications -  37
Citations -  670

Xiaozhou Mou is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 13, co-authored 18 publications receiving 479 citations. Previous affiliations of Xiaozhou Mou include Zhejiang California International NanoSystems Institute.

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Human Menstrual Blood-Derived Stem Cells Ameliorate Liver Fibrosis in Mice by Targeting Hepatic Stellate Cells via Paracrine Mediators

TL;DR: Investigating the therapeutic effects of MenSC transplantation in a carbon tetrachloride‐induced mouse model of liver fibrosis revealed that MenSCs markedly improved liver function, attenuated collagen deposition, and inhibited activated hepatic stellate cells up to 2 weeks after transplantation.
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Menstrual blood-derived mesenchymal stem cells differentiate into functional hepatocyte-like cells.

TL;DR: MenSCs may serve as an ideal, easily accessible source of material for tissue engineering and cell therapy of liver tissues and it was shown that MenSC-derived HLC transplantation could restore the serum ALB level and significantly suppressed transaminase activity of liver injury animals.
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Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis

TL;DR: A novel role of tyrosine phosphatase Shp2 in surfactant homeostasis is identified, and deregulation of Shp1 triggers spontaneous pulmonary fibrosis with minimal inflammation.
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A dynamic real-time method for monitoring epithelial barrier function in vitro.

TL;DR: This work introduces an electronic impedance-based analysis using a real-time xCELLigence system to record the dynamic processes of ethanol-induced intestinal barrier dysfunction and identifies the in vitro roles of the inducible nitric oxide synthase inhibitor, epithelial growth factor, tyrosine kinases, and phosphatases in regulating epithelial barrier function in response to ethanol administration.
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Prevalence of JC virus in Chinese patients with colorectal cancer.

TL;DR: JCV infection is frequently present in colorectal tumor tissues of CRC patients and the JCV prevalence in PB samples was significantly associated with the J CV status in tissue samples, whether PB JCV detection can serve as a marker for JCV status of CRC requires further study.