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Xiauyu Wen
Researcher at Osaka University
Publications - 2
Citations - 63
Xiauyu Wen is an academic researcher from Osaka University. The author has contributed to research in topics: Regulation of gene expression & Gene delivery. The author has an hindex of 2, co-authored 2 publications receiving 55 citations.
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Journal ArticleDOI
CD44 participates in IP-10 induction in cells in which hepatitis C virus RNA is replicating, through an interaction with Toll-like receptor 2 and hyaluronan.
Takayuki Abe,Takasuke Fukuhara,Xiauyu Wen,Akinori Ninomiya,Kohji Moriishi,Yoshihiko Maehara,Osamu Takeuchi,Taro Kawai,Shizuo Akira,Yoshiharu Matsuura +9 more
TL;DR: The results suggest that endogenous expression of HA in hepatocytes in CHC patients participates in IP-10 production through an engagement of TLR2 and CD44.
Journal ArticleDOI
Innate Immune Response Induced by Baculovirus Attenuates Transgene Expression in Mammalian Cells
Chikako Ono,Akinori Ninomiya,Satomi Yamamoto,Takayuki Abe,Xiauyu Wen,Takasuke Fukuhara,Miwa Sasai,Masahiro Yamamoto,Tatsuya Saitoh,Takashi Satoh,Taro Kawai,Ken Ishii,Shizuo Akira,Toru Okamoto,Yoshiharu Matsuura +14 more
TL;DR: The results indicate that innate immune responses induced by infection with baculovirus attenuate transgene expression, and this characteristic might be useful for a selective gene transduction into cells with impaired innate immunity arising from infection with various viruses.