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Xinping Zhang
Researcher at Beijing University of Technology
Publications - 380
Citations - 9846
Xinping Zhang is an academic researcher from Beijing University of Technology. The author has contributed to research in topics: Laser & Plasmon. The author has an hindex of 47, co-authored 328 publications receiving 8226 citations. Previous affiliations of Xinping Zhang include University of California, Los Angeles & University of Rochester Medical Center.
Papers
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Journal ArticleDOI
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
Xinping Zhang,Edward M. Schwarz,Donald A. Young,J. Edward Puzas,Randy N. Rosier,Regis J. O'Keefe +5 more
TL;DR: It is demonstrated that COX-2 plays an essential role in both endochondral and intramembranous bone formation during skeletal repair and regulates the induction of cbfa1 and osterix to mediate normal skeletal repair.
Journal ArticleDOI
Periosteal Progenitor Cell Fate in Segmental Cortical Bone Graft Transplantations: Implications for Functional Tissue Engineering
Xinping Zhang,Chao Xie,Angela S.P. Lin,Hiromu Ito,Hani A. Awad,Hani A. Awad,Jay R. Lieberman,Paul T. Rubery,Edward M. Schwarz,Regis J. O'Keefe,Robert E. Guldberg +10 more
TL;DR: In this paper, a segmental femoral bone graft model was used to show the essential role of donor periosteal progenitor cells in bone graft healing, and a cell-based, adenovirus-mediated gene therapy approach was applied to engraft BMP-2 producing bone marrow stromal cells onto devitalized allografts.
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Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts
TL;DR: The findings with cyclooxygenase knockout cells confirm recent reports that some of the antiproliferative and antineoplastic effects of NSAIDs are independent of the inhibition of either COX-1 orCOX-2, and suggest that the involvement of the cyclo oxygengenases in tumorigenesis may occur at later steps.
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Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
Hiromu Ito,Hiromu Ito,Mette Koefoed,Prarop Tiyapatanaputi,Kirill Gromov,J. Jeffrey Goater,Jonathan J. Carmouche,Xinping Zhang,Paul T. Rubery,Joseph E. Rabinowitz,R. Jude Samulski,Takashi Nakamura,Kjeld Søballe,Regis J. O'Keefe,Brendan F. Boyce,Edward M. Schwarz +15 more
TL;DR: It is found that RANKL and VEGF are necessary and sufficient for efficient autograft remodeling and can be transferred using rAAV to revitalize structural allografts.
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Regulation of chondrogenesis and chondrocyte differentiation by stress
TL;DR: An overview of the processes of chondrogenesis and endochondral ossification and their control at the molecular level is provided and a summary of the influence of the most well-understood normal and pathologic stressors on the differentiation program is presented.