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Xinsheng Yao
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 1
Citations - 7
Xinsheng Yao is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Galectin & Alanine. The author has an hindex of 1, co-authored 1 publications receiving 5 citations.
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Engineering of a 3'-sulpho-Galβ1-4GlcNAc-specific probe by a single amino acid substitution of a fungal galectin.
Dan Hu,Hang Huang,Hiroaki Tateno,Shin-ichi Nakakita,Takashi Sato,Hisashi Narimatsu,Xinsheng Yao,Jun Hirabayashi +7 more
TL;DR: In the course of molecular engineering of a fungal galectin from Agrocybe cylindracea, a single substitution of Glu86 with alanine resulted in acquisition of specific binding for the 3'-sulpho-Galβ1-4GlcNAc structure, and extensive glyco-technological analysis revealed that this property was obtained in a 'loss of function' manner.