X
Xu Qi Chen
Researcher at University of Geneva
Publications - 8
Citations - 2351
Xu Qi Chen is an academic researcher from University of Geneva. The author has contributed to research in topics: Cancer & Microsatellite instability. The author has an hindex of 7, co-authored 8 publications receiving 2278 citations.
Papers
More filters
Journal ArticleDOI
Microsatellite alterations in plasma DNA of small cell lung cancer patients.
Xu Qi Chen,Maurice Stroun,Jean-Luc Magnenat,Laurent P. Nicod,Anne-Marie Kurt,Jacqueline Lyautey,Christine Lederrey,Philippe Anker +7 more
TL;DR: If confirmed in larger studies, microsatellite analysis of plasma DNA might constitute a new tool for tumor staging, management and, possibly, detection.
Journal ArticleDOI
Detection of circulating tumour DNA in the blood (plasma/serum) of cancer patients.
TL;DR: The results obtained in many different cancers have opened a new research area indicating that plasma DNA might eventually be a suitable target for the development of non-invasive diagnostic, prognostic and follow-up tests for cancer.
Journal ArticleDOI
The origin and mechanism of circulating DNA.
Maurice Stroun,P. A. Maurice,Valery Vasioukhin,Jacqueline Lyautey,C. Lederrey,François Lefort,Alain Rossier,Xu Qi Chen,Philippe Anker +8 more
TL;DR: Plasma DNA levels are not only greater in cancer patients than in normal subjects, but also correlate inversely with outcome and tend to fall with effective treatment, which suggests that tumor-related DNA is the predominant subtype in at least some cancer patients.
Journal ArticleDOI
K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer
Philippe Anker,François Lefort,Valeri Vasioukhin,Jacqueline Lyautey,C. Lederrey,Xu Qi Chen,Maurice Stroun,Hugh Mulcahy,M. J. G. Farthing +8 more
TL;DR: K-ras abnormalities can be detected in circulating DNA extracted from the plasma specimens of patients with colorectal cancer and if these results are confirmed in larger studies, genetic analysis of plasma DNA may have clinical applications in the future.
Journal Article
Telomerase RNA as a Detection Marker in the Serum of Breast Cancer Patients
Xu Qi Chen,Hervé Bonnefoi,Marie-Françoise Pelte,Jacqueline Lyautey,C. Lederrey,Sina Movarekhi,Pierre Schaeffer,Hugh Mulcahy,Pierre Meyer,Maurice Stroun,Philippe Anker +10 more
TL;DR: RNA is detectable in the serum of breast cancer patients and that tumor-derived mRNA can be extracted and amplified using RT-PCR, even in patients with localized disease, may have implications for cancer diagnosis and follow-up in the future.