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Xue-Gong Fan
Researcher at Central South University
Publications - 41
Citations - 664
Xue-Gong Fan is an academic researcher from Central South University. The author has contributed to research in topics: HBsAg & Hepatitis B virus. The author has an hindex of 12, co-authored 41 publications receiving 432 citations.
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Journal ArticleDOI
CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression.
TL;DR: The circRNA-5692–miR-328-5p–DAB2IP regulatory pathway inhibits the progression of HCC and may provide potential new targets for the diagnosis and therapy of H CC.
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A novel lncRNA, TCONS_00006195, represses hepatocellular carcinoma progression by inhibiting enzymatic activity of ENO1
Songman Yu,Ning Li,Ze-Bing Huang,Ruochan Chen,Panpan Yi,Rui Kang,Daolin Tang,Xingwang Hu,Xue-Gong Fan +8 more
TL;DR: Results suggest that lncRNA-6195 represses the growth of HCC by inhibiting the enzymatic activity of ENO1, and can serve as a basis for the development of novel strategies to hinder HCC.
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SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival.
Jiaxin Liu,Q. H. Zeng,P. G. Cao,Dan Xie,Fei Yang,L. Y. He,Y. B. Dai,Jianjun Li,Xiaoming Liu,H. L. Zeng,Xue-Gong Fan,L. Liu,Yuxing Zhu,Liansheng Gong,Yaxin Cheng,J. D. Zhou,J. Hu,Hao Bo,Z. Z. Xu,Ke Cao +19 more
TL;DR: Mechanistic investigations showed that SPAG5 promotes proliferation and suppresses apoptosis in BUC at least partially via upregulating Wnt3 through activating the AKT/mTOR signaling pathway, and the importance of the SPAg5/AKT-mTOR/Wnt3 axis identified in B UC cell models was confirmed.
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Radiation-promoted CDC6 protein stability contributes to radioresistance by regulating senescence and epithelial to mesenchymal transition.
Xiaohui Yu,Youhong Liu,Linglong Yin,Peng Yongbo,Yuchong Peng,Yingxue Gao,Bowen Yuan,Qianling Zhu,Tuoyu Cao,Bowen Xie,Lun-Quan Sun,Yan Chen,Zhicheng Gong,Yuanzheng Qiu,Xue-Gong Fan,Xiong Li +15 more
TL;DR: Cell models for IR-induced senescence, apoptosis resistance, and EMT, three major mechanisms by which radioresistance develops are described, suggesting that CDC6highKI67low represents a new diagnostic marker of radiosensitivity, and CDC6 represents anew therapeutic target for cancer radiosensitization.
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Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response
TL;DR: A novel mechanism of theHBx-mediated oncogenesis is revealed and provides a basis for potential HBx-targeted therapeutic intervention of HCC.