Y
Y. Giudicelli
Researcher at Paris Descartes University
Publications - 13
Citations - 565
Y. Giudicelli is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Adipose tissue & Adipogenesis. The author has an hindex of 11, co-authored 13 publications receiving 541 citations.
Papers
More filters
Journal ArticleDOI
Opposite Effects of Androgens and Estrogens on Adipogenesis in Rat Preadipocytes: Evidence for Sex and Site-Related Specificities and Possible Involvement of Insulin-Like Growth Factor 1 Receptor and Peroxisome Proliferator-Activated Receptorγ 21
TL;DR: This study demonstrates that, in rat preadipocytes kept in primary culture and chronically exposed to sex hormones, androgens elicit an anti-ipogenic effect, whereas estrogens behave as proadipogenic hormones.
Journal ArticleDOI
Direct in vitro effects of androgens and estrogens on ob gene expression and leptin secretion in human adipose tissue
Florence Machinal-Quelin,Marie-Noëlle Dieudonné,René Pecquery,Marie-Christine Leneveu,Y. Giudicelli +4 more
TL;DR: The results suggest that the sexual dimorphism of leptinemia in humans is mainly owing to the estrogen receptor-dependent stimulation of leptin expression in adipose tissue by estrogens and estrogen precursors in women.
Journal ArticleDOI
Semi-quantitative RT-PCR for comparison of mRNAs in cells with different amounts of housekeeping gene transcripts.
TL;DR: This procedure enables transcripts to be compared when the differentiation process affects the transcription pattern of the beta-actin housekeeping gene, a commonly used internal standard, and is sensitive and avoids constructing internal competitive RNA standards.
Journal ArticleDOI
Control of rat preadipocyte adipose conversion by ovarian status: regional specificity and possible involvement of the mitogen-activated protein kinase-dependent and c-fos signaling pathways.
TL;DR: It is demonstrated that adipogenesis is site-specifically controlled by the ovarian status in the rat and suggests that ovariectomy-induced obesity (mainly abdominal) could be related to changes in some of the signaling pathways controlling adipogenesis in intraabdominal preadipocytes.
Journal ArticleDOI
Site-related specificities of the control by androgenic status of adipogenesis and mitogen-activated protein kinase cascade/c-fos signaling pathways in rat preadipocytes.
TL;DR: The results suggest that androgenic status affects adipogenesis from deep intraabdominal preadipocytes through alterations of some components of the MAP kinase cascade/Fos signaling pathways.