Y. S. Huang

TL;DR: The results showed that animals fed higher proportions of POL consistently contained higher levels of dihomo-γ-linolenic acid (DGLA) and lower levels of arachidonic acid (AA), suggesting that EPA but not DHA in fish oil exerts an inhibitory effect on the conversion of DGLA to AA.

TL;DR: Male rats were fed on a fat-free diet for 8 weeks and then switched to diets containing 10% hydrogenated coconut oil (HCO), safflower oil (SFO) or evening primrose oil (EPO), suggesting that conversion of linoleic acid to 18∶3n−6 and possibly to further metabolites may be important for the cholesterol-lowering effect of polyunsaturates.

TL;DR: In this article, essential fatty acids were estimated in plasma, red blood cells and liver total phospholipids in rats, mice, hamsters, guinea pigs, rabbits and humans.

TL;DR: The high EPA levels in Eskimos and West Coast Indians are related to diet, and the low AA levels, in contrast, are probably genetically determined.

TL;DR: It is proposed that in schizophrenia mutant desaturases are present which prefer the n6 series of EFAs and Heterozygotes carrying such a mutant gene would have an advantage over either form of homozygote since they would be better able to cope with variations in dietary intake of n3 and n6 EFAs.