Y
Ya Hua
Researcher at University of Michigan
Publications - 235
Citations - 11100
Ya Hua is an academic researcher from University of Michigan. The author has contributed to research in topics: Intracerebral hemorrhage & Thrombin. The author has an hindex of 54, co-authored 221 publications receiving 9310 citations. Previous affiliations of Ya Hua include Fudan University & Zhejiang University.
Papers
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Journal ArticleDOI
Intracerebral haemorrhage: mechanisms of injury and therapeutic targets
Richard F. Keep,Ya Hua,Guohua Xi +2 more
TL;DR: Important advances have been made in animal models of this disorder and in the understanding of mechanisms underlying brain injury after haemorrhage, and several therapeutic targets have subsequently been identified that are now being pursued in clinical trials.
Journal ArticleDOI
Behavioral Tests After Intracerebral Hemorrhage in the Rat
TL;DR: A battery of sensorimotor function tests were used to examine the neurological effects of ICH in the rat and to examine which components of the hematoma are involved in generating those effects.
Journal ArticleDOI
Iron and Iron-Handling Proteins in the Brain After Intracerebral Hemorrhage
TL;DR: The iron overload and upregulation of iron-handling proteins, including transferrin, transferrin receptor, and ferritin, in the brain after ICH suggest that iron could be a target for ICH therapy.
Journal ArticleDOI
Brain injury after intracerebral hemorrhage: the role of thrombin and iron.
TL;DR: The role of thrombin and iron in ICH-induced injury is reviewed and it is suggested that these mechanisms may provide new therapeutic targets.
Journal ArticleDOI
Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhage
Jimin Wu,Ya Hua,Richard F. Keep,Timothy J Schallert,Timothy J Schallert,Julian T. Hoff,Guohua Xi +6 more
TL;DR: In this paper, the authors investigated whether erythrocyte lysis after intracerebral hemorrhage (ICH) might result in oxidative brain damage in male Sprague-Dawley rats.