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Yan Fan
Researcher at Ocean University of China
Publications - 22
Citations - 633
Yan Fan is an academic researcher from Ocean University of China. The author has contributed to research in topics: Gelatin & Peptide. The author has an hindex of 10, co-authored 22 publications receiving 439 citations.
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Characterization of acid-soluble collagen from the skin of walleye pollock (Theragra chalcogramma)
Mingyan Yan,Bafang Li,Xue Zhao,Guoyan Ren,Yongliang Zhuang,Hu Hou,Xiukun Zhang,Li Chen,Yan Fan +8 more
TL;DR: In this article, acid-soluble collagen (ASC) was extracted from the skin of walleye pollock ( Theragra chalcogramma) and partially characterized It exhibited a maximum absorbance at 220nm, but little absorbance near to 280nm Amino acid composition and SDS-PAGE suggested that the collagen might be classified as type I collagen Moreover, FTIR investigations showed the existence of helical arrangements of collagen
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A novel calcium-binding peptide from Antarctic krill protein hydrolysates and identification of binding sites of calcium-peptide complex.
TL;DR: Molecular dynamic simulation showed the conformation of peptide was markedly varied, and the distance between calcium ion and Gln and Ile residues was changing all the time, however, the distance around carboxyl oxygen of arginine residues was not changed significantly, and Identified peptide can be used as a novel calcium supplement.
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Protective effect of gelatin peptides from pacific cod skin against photoaging by inhibiting the expression of MMPs via MAPK signaling pathway.
TL;DR: G gelatin hydrolysate (CH) derived from pacific cod skin can effectively protect against UV irradiation-induced skin photoaging by inhibiting the expression and the activity of MMPs.
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Purification and identification of immunomodulating peptides from enzymatic hydrolysates of Alaska pollock frame.
TL;DR: The results demonstrated that the APF proteins hydrolysates prepared by trypsin could serve as a source of peptides with immunomodulating activity and provided a scientific basis for the preparation of immunommodulating peptides.
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Immunomodulatory activity of Alaska pollock hydrolysates obtained by glutamic acid biosensor – Artificial neural network and the identification of its active central fragment
TL;DR: Glutamic acid biosensor and artificial neural network was employed to monitor the hydrolysis of Alaska pollock protein for production of immunomodulatory peptides, which significantly enhanced humoral, cellular, and non-specific immunity in immunosuppressed mice.