Yan-Hui Fu

TL;DR: 17-O-methyl-19-(Z)-naucline (1) showed significant inhibitory activity on nitric oxide production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells in vitro with an IC50 value of 3.6 μM.

TL;DR: A new monoterpenoid indole alkaloid, 10-methoxyakuammidine, together with four known alkaloids, were isolated from the stems and leaves of Ochrosia elliptica and exhibited inhibitory effects with IC50 values comparable to those of cisplatin.

TL;DR: A new polyoxygenated cyclohexene derivative, artahainanol A (1), together with three known analogues (2–4), was isolated from the stems and leaves of Artabotrys hainanensis and showed significant inhibitory effects against various human cancer cell lines.

TL;DR: A new abietane diterpenoid, tripterregeline A (1) was isolated from the roots of Tripterygium regelii and showed significant inhibitory effects against various human cancer cell lines with IC50 values ranging from 0.58 to 21.06 μM.

TL;DR: Fissistigmine A represents the first example of a novel naturally occurring morphinandienone alkaloid with a unique cleavage of the C-9−N-17 bond and anti-rheumatoid arthritis activities via examining their anti-proliferative effects on synoviocytes in vitro.