Y
Yan Wang
Researcher at The Chinese University of Hong Kong
Publications - 2
Citations - 47
Yan Wang is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Hyperpolarization (biology) & Phosphorylation. The author has an hindex of 2, co-authored 2 publications receiving 43 citations.
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Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation
TL;DR: A novel role of the NO-cGMP-PKG pathway is demonstrated in the inhibition of 11,12-EET-induced smooth muscle hyperpolarization and relaxation via PKG-mediated phosphorylation of TRPC1.1.
Journal ArticleDOI
Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer.
Peng Zhang,Dongxu He,Zhen Chen,Qiongxi Pan,Fangfang Du,Xian Zang,Yan Wang,Chunlei Tang,Hong Li,He Lu,Xiaoqiang Yao,Jian Jin,Xin Ma,Xin Ma +13 more
TL;DR: It is demonstrated that chemotherapy induces functional tumor-derived endothelial microvessels by mediating Notch signaling and VEGF signaling, and may provide new targets for anti-angiogenesis therapy in breast cancer.