Y
Yanan Sun
Researcher at Harbin Medical University
Publications - 60
Citations - 2088
Yanan Sun is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Medicine & microRNA. The author has an hindex of 20, co-authored 51 publications receiving 1719 citations.
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Long intergenic noncoding RNA HOTAIR is overexpressed and regulates PTEN methylation in laryngeal squamous cell carcinoma.
TL;DR: Results suggest that the oncogenic role of HOTAIR in LSCC is related to promotion of PTEN methylation and could serve as a marker for LSCC prognosis and a potential target for therapeutic intervention.
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Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma
TL;DR: Serum exosomal miR-21 and HOTAIR were significantly correlated with clinical parameters of LSCC, and combined evaluation of their serum expressions may be a valuable biomarker to screen LSCC and might be a promising predicting tool for LSCC patient.
Journal Article
Circular RNA: a novel biomarker for progressive laryngeal cancer.
Lijia Xuan,Lingmei Qu,Han Zhou,Peng Wang,Haoyang Yu,Tianyi Wu,Xin Wang,Qiuying Li,Linli Tian,Ming Liu,Yanan Sun +10 more
TL;DR: The data suggest that circRNAs play an important role in the tumorigenesis of LS CC and may serve as novel and stable biomarkers for the diagnosis and progress of LSCC.
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Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway.
Peng Wang,Tianyi Wu,Han Zhou,Qianqian Jin,Guoqing He,Haoyang Yu,Lijia Xuan,Xin Wang,Linli Tian,Yanan Sun,Ming Liu,Lingmei Qu +11 more
TL;DR: NEAT1 plays an oncogenic role in the tumorigenesis of LSCC and may serve as a potential target for therapeutic intervention in patients with neck nodal metastasis or advanced clinical stage.
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Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis.
Tianyi Wu,Lingmei Qu,Guoqing He,Linli Tian,Liang Li,Han Zhou,Qian Jin,Jingyuan Ren,Yu Wang,Jingting Wang,Xuan Kan,Ming Liu,Jia Shen,Mian Guo,Yanan Sun +14 more
TL;DR: It is demonstrated that the lncRNA H19 promoted LSCC progression via miR-148a-3p and DNMT1 and cellular DNA methylation levels were inhibited by both H19 overexpression and H19 knockdown.