J
Jianguang Lu
Researcher at Harbin Medical University
Publications - 14
Citations - 605
Jianguang Lu is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Cell cycle & Apoptosis. The author has an hindex of 11, co-authored 13 publications receiving 480 citations.
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Journal ArticleDOI
Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma
TL;DR: Serum exosomal miR-21 and HOTAIR were significantly correlated with clinical parameters of LSCC, and combined evaluation of their serum expressions may be a valuable biomarker to screen LSCC and might be a promising predicting tool for LSCC patient.
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Synthesis of Zinc oxide nanoparticles from Marsdenia tenacissima inhibits the cell proliferation and induces apoptosis in laryngeal cancer cells (Hep-2).
Yu Wang,Yayuan Zhang,Yan Guo,Jianguang Lu,Vishnu Priya Veeraraghavan,Surapaneni Krishna Mohan,Chao Wang,Xiaoguang Yu +7 more
TL;DR: Biosynthesis of Zinc oxide nanoparticles from natural plants stands as a promising nanodrug delivery system in cancer therapeutics and its anti cancer potency was assessed against in vitro laryngeal cancer cell line Hep-2, suggesting that biosynthesized M.t-ZnONPs, a valid anticancer strategy in treating various cancer, is an effective anticancer agent.
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Down-Regulation of miR-129-5p Inhibits Growth and Induces Apoptosis in Laryngeal Squamous Cell Carcinoma by Targeting APC
Minghua Li,Linli Tian,Lin Wang,Hongchao Yao,Jiarui Zhang,Jianguang Lu,Yanan Sun,Xu Gao,Hui Xiao,Ming Liu +9 more
TL;DR: The results suggest miR-129-5p functions as an oncogene in LSCC by repressing APC and is a potential therapeutic target for LSCC.
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Is E-cadherin immunoexpression a prognostic factor for head and neck squamous cell carcinoma (HNSCC)? A systematic review and meta-analysis
TL;DR: An important piece of evidence is given that aberrant E-cadherin expression was associated with a poor prognosis in patients with HNSCC.
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MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma.
TL;DR: The results suggest that miR-205 may play as a tumor suppressor in LSCC, probably by targeting Bcl-2 and serve as a potential target for therapeutic intervention.