Y
Yang Jin
Researcher at Huazhong University of Science and Technology
Publications - 103
Citations - 4970
Yang Jin is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Lung cancer. The author has an hindex of 20, co-authored 69 publications receiving 3282 citations.
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Journal ArticleDOI
Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.
Yeming Wang,Yeming Wang,Dingyu Zhang,Guanhua Du,Ronghui Du,Jianping Zhao,Yang Jin,Shouzhi Fu,Ling Gao,Zhenshun Cheng,Qiaofa Lu,Yi Hu,Guangwei Luo,Ke Wang,Yang Lu,Huadong Li,Shuzhen Wang,Shunan Ruan,Chengqing Yang,Chunlin Mei,Yi Wang,Dan Ding,Feng Wu,Xin Tang,Xianzhi Ye,Yingchun Ye,Bing Liu,Jie Yang,Wen Yin,Aili Wang,Guohui Fan,Fei Zhou,Zhibo Liu,Xiaoying Gu,Jiuyang Xu,Lianhan Shang,Lianhan Shang,Yi Zhang,Lianjun Cao,Guo Tingting,Yan Wan,Hong Qin,Yushen Jiang,Thomas Jaki,Thomas Jaki,Frederick G. Hayden,Peter Horby,Bin Cao,Chen Wang +48 more
TL;DR: In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits, however, the numerical reduction in time to clinical improvement in those treated earlier requires confirmation in larger studies.
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Fasting blood glucose at admission is an independent predictor for 28-day mortality in patients with COVID-19 without previous diagnosis of diabetes: a multi-centre retrospective study.
Sufei Wang,Pei Ma,Shujing Zhang,Siwei Song,Zhihui Wang,Yanling Ma,Juanjuan Xu,Feng Wu,Limin Duan,Zhengrong Yin,Huilin Luo,Nian Xiong,Man Xu,Tianshu Zeng,Yang Jin +14 more
TL;DR: Examination of the relationship between fasting blood glucose (FBG) and 28-day mortality in coronavirus disease 2019 (COVID-19) patients not previously diagnosed as having diabetes found that FBG ≥7.0 mmol/l at admission is an independent predictor for 28- day mortality in patients with CO VID-19 without previous diagnosis of diabetes.
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Nanoparticles Targeting Macrophages as Potential Clinical Therapeutic Agents Against Cancer and Inflammation.
Guorong Hu,Mengfei Guo,Juanjuan Xu,Feng Wu,Jinshuo Fan,Qi Huang,Guanghai Yang,Zhilei Lv,Xuan Wang,Yang Jin +9 more
TL;DR: In this article, the authors present a brief background information of nanoparticles as drug carriers, including but not limited to the types of nanomaterials, their biological properties and their advantages in clinical application.
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Autologous tumor cell–derived microparticle-based targeted chemotherapy in lung cancer patients with malignant pleural effusion
Mengfei Guo,Feng Wu,Guorong Hu,Lian Chen,Juanjuan Xu,Pingwei Xu,Xuan Wang,Yumei Li,Shuqing Liu,Shuai Zhang,Qi Huang,Jinshuo Fan,Zhilei Lv,Mei Zhou,Limin Duan,Tingting Liao,Guanghai Yang,Ke Tang,Bifeng Liu,Xiaofei Liao,Xiaonan Tao,Yang Jin +21 more
TL;DR: The initial experience with TMPs-MTX in advanced lung cancer with MPE suggests that ATMPs targeting malignant cells and the immunosuppressive microenvironment may be a promising therapeutic platform for treating malignancies.
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Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis
TL;DR: Emerging evidence indicates that IL‐17 not only has an oncogenic role in tumorigenesis by regulating tumor angiogenesis and enhancing tumor immune evasion but also exerts anti‐tumor functions by enhancing natural killer cells and cytotoxic T lymphocytes activation and through the recruitment of neutrophils, NK cells and CD4+ and CD8+ T cells to tumor tissue.