Y
Yang Wang
Researcher at Sichuan University
Publications - 13
Citations - 421
Yang Wang is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 4, co-authored 9 publications receiving 54 citations.
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mRNA vaccine: a potential therapeutic strategy.
TL;DR: In this article, the molecular biology of mRNA vaccines and underlying anti-virus and anti-tumor mechanisms, with an introduction of their immunological phenomena, delivery strategies, their importance on Corona Virus Disease 2019 (COVID-19) and related clinical trials against cancer and viral diseases.
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cGAS-STING pathway in cancer biotherapy
TL;DR: The article will discuss the activation of the cGAS-STING pathway and underlying mechanisms, with an introduction of cGas- STING agonists, related clinical trials and agonist delivery systems.
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Role of lysosomes in physiological activities, diseases, and therapy
TL;DR: In this article, the physiological function of lysosomes and how the homeostasis of LBSs is disrupted in several diseases, including atherosclerosis, neurodegenerative diseases, autoimmune disorders, pancreatitis, lyssoomal storage disorders, and malignant tumors.
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Role of the CCL2-CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting
TL;DR: The role of the CCL2-CCR2 signalling axis in tumorigenesis and highlight recent studies on CCL 2-CCR2 targeted therapy, focusing on preclinical studies and clinical trials as mentioned in this paper.
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Inhibition of FGF-FGFR and VEGF-VEGFR signalling in cancer treatment
TL;DR: In this paper, the authors discuss the FGF-FGFR signalling pathway, the VEGF-VEGFR signaling pathway, and the rationale of combining these two signalling pathways and recent small-molecule FGFR/veGFR inhibitors based on clinical trials.