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Yang-Yang Zhao
Researcher at Chengdu Medical College
Publications - 10
Citations - 111
Yang-Yang Zhao is an academic researcher from Chengdu Medical College. The author has contributed to research in topics: Medicine & Pyroptosis. The author has an hindex of 2, co-authored 5 publications receiving 18 citations.
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Journal ArticleDOI
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549.
Shi-Hua Deng,Dong-Ming Wu,Li Li,Teng Liu,Ting Zhang,Jing Li,Ye Yu,Miao He,Yang-Yang Zhao,Rong Han,Ying Xu +10 more
TL;DR: In this article, the effect of miR-324-3p on lung adenocarcinoma cell line A549 resistant to cis-diamminedichloroplatinum II (DDP), aka cisplatin was investigated.
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Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
TL;DR: It is found that bixin significantly improved the symptoms and pathology in EAE mice, reduced the release of inflammatory cytokines TNF-α,IL-6, IL-8, Il-17, and IFN-γ, and increased the expression of the anti-inflammatory cytokine IL-10, and taken together these results indicate thatbixin is a promising therapeutic candidate for treatment of MS.
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CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition
Ting Zhang,Dong-Ming Wu,Peng Luo,Teng Liu,Rong Han,Shi-Hua Deng,M. G. M O R S He,Yang-Yang Zhao,Ying Xu +8 more
TL;DR: In this paper , the authors established the expression profiles of 1,875 dysregulated circRNAs in non-irradiated and irradiated A549 cells and identified circNEIL3 as a significantly downregulated circRNA.
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AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway.
Miao He,Dong-Ming Wu,Yang-Yang Zhao,Ye Yu,Shi-Hua Deng,Teng Liu,Ting Zhang,Jing Li,Feng Wang,Ying Xu +9 more
TL;DR: Zhang et al. as mentioned in this paper evaluated the effects of the autophagy activator AZD8055 on experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS).
Journal ArticleDOI
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia
Dong-Ming Wu,M. G. M O R S He,Yang-Yang Zhao,Shi-Hua Deng,Teng Liu,Ting Zhang,Feng Zhang,Yuandong Wang,Ying Xu +8 more
TL;DR: In this article , the effect of radiation exposure on Aspergillus fumigatus infection and the associated mechanisms was explored in a mouse model and the results indicated that activation of NLRP3 inflammasomes following radiation exposure increased susceptibility to infection.