Y
Yanhong Deng
Researcher at Yale University
Publications - 122
Citations - 2363
Yanhong Deng is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 22, co-authored 72 publications receiving 1600 citations. Previous affiliations of Yanhong Deng include Yale Cancer Center.
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Journal ArticleDOI
Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA
Sarah B. Goldberg,Azeet Narayan,Adam J. Kole,Roy H. Decker,Jimmitti Teysir,Nicholas Carriero,Angela Lee,Roxanne Nemati,Sameer K. Nath,Shrikant Mane,Yanhong Deng,Nitin Sukumar,Daniel Zelterman,Daniel J. Boffa,Katerina Politi,Scott N. Gettinger,Lynn D. Wilson,Roy S. Herbst,Abhijit A. Patel +18 more
TL;DR: A drop in ctDNA level is an early marker of therapeutic efficacy and predicts prolonged survival in patients treated with immune checkpoint inhibitors for NSCLC.
Journal ArticleDOI
Abnormal Liver Tests in COVID-19: A Retrospective Observational Cohort Study of 1,827 Patients in a Major U.S. Hospital Network.
TL;DR: The coronav virus‐19 disease (COVID‐19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 virus, is associated with significant morbidity and mortality attributable to pneumonia, acute respiratory distress syndrome, and multiorgan failure.
Journal ArticleDOI
Final analysis of a phase II study of modified FOLFIRINOX in locally advanced and metastatic pancreatic cancer
Stacey Stein,Edward Samuel James,Yanhong Deng,Xiangyu Cong,Jeremy S. Kortmansky,Jia Li,Carol Staugaard,Doddamane Indukala,Ann Marie Boustani,Vatsal Patel,Charles Cha,Ronald R. Salem,Bryan W. Chang,Howard S. Hochster,Jill Lacy +14 more
TL;DR: In this first prospective study of modified FOLFIRINOX in MPC and LAPC, decreased AEs are observed compared with historical control patients and the efficacy appears comparable with FOL FIRINOX, and support the continued use of F OLFIRinoX in this setting.
Journal ArticleDOI
Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men
Brian T. Clark,Petr Protiva,Petr Protiva,Anil B. Nagar,Anil B. Nagar,Avlin B. Imaeda,Avlin B. Imaeda,Maria M. Ciarleglio,Yanhong Deng,Loren Laine,Loren Laine +10 more
TL;DR: Patients with BBPS scores of 2 or 3 for all colon segments have adequate bowel preparation for the detection of adenomas larger than 5 mm and should return for screening or surveillance colonoscopy at standard guideline-recommended intervals.
Journal ArticleDOI
Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells.
Chandra Sekhar Boddupalli,Noffar Bar,Krishna Kadaveru,Michael Krauthammer,Natopol Pornputtapong,Zifeng Mai,Stephan Ariyan,Deepak Narayan,Harriet M. Kluger,Yanhong Deng,Rakesh Verma,Rituparna Das,Antonella Bacchiocchi,Ruth Halaban,Mario Sznol,Madhav V. Dhodapkar,Madhav V. Dhodapkar,Kavita M. Dhodapkar +17 more
TL;DR: It is suggested that the TRM subset of TILs may be the major target of ICP blockade and illustrate interlesional diversity of tissue-resident TCRs within individual metastases, which did not equilibrate between metastases and may differentially affect the outcome of immune therapy at each site.