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Yared Gurmu
Researcher at Brigham and Women's Hospital
Publications - 20
Citations - 793
Yared Gurmu is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Enalapril. The author has an hindex of 12, co-authored 20 publications receiving 489 citations. Previous affiliations of Yared Gurmu include Boston Children's Hospital & Harvard University.
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Journal ArticleDOI
Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial.
Nicholas A Marston,Frederick K. Kamanu,Francesco Nordio,Yared Gurmu,Carolina Roselli,Carolina Roselli,Peter S. Sever,Terje R. Pedersen,Anthony C Keech,Huei Wang,Armando Lira Pineda,Robert P. Giugliano,Steven A. Lubitz,Steven A. Lubitz,Patrick T. Ellinor,Patrick T. Ellinor,Marc S. Sabatine,Christian T. Ruff +17 more
TL;DR: Patients with high genetic risk, regardless of clinical risk, had a high event rate and derived the greatest relative and absolute benefit from evolocumab, which mitigated this risk.
Journal ArticleDOI
Clinical Outcomes in Patients With Acute Decompensated Heart Failure Randomly Assigned to Sacubitril/Valsartan or Enalapril in the PIONEER-HF Trial
David A. Morrow,Eric J. Velazquez,Adam D. DeVore,Akshay S. Desai,Carol I. Duffy,Andrew P. Ambrosy,Andrew P. Ambrosy,Yared Gurmu,Kevin McCague,Ricardo Rocha,Eugene Braunwald +10 more
TL;DR: The primary results of the randomized double-blind PIONEER-HF trial were reported demonstrating that, in comparison with enalapril, in patients hemodynamically stabilized during hospitalization for ADHF, sacubitril/ valsartan achieved a greater reduction in N-terminal pro-brain natriuretic peptide concentration, was safe and well-tolerated.
Journal ArticleDOI
Heart Failure Risk Stratification and Efficacy of Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Type 2 Diabetes Mellitus.
David D. Berg,Stephen D. Wiviott,Benjamin M. Scirica,Yared Gurmu,Ofri Mosenzon,Sabina A. Murphy,Deepak L. Bhatt,Lawrence A. Leiter,Darren K. McGuire,John P.H. Wilding,Per Johanson,Peter A. Johansson,Anna Maria Langkilde,Itamar Raz,Eugene Braunwald,Marc S. Sabatine +15 more
TL;DR: Patients with type 2 diabetes mellitus are at increased risk of developing heart failure and Sodium-glucose cotransporter-2 inhibitors reduce the risk of hospitalization for heart failure.
Journal ArticleDOI
Bone Mineral Density in Children and Adolescents with Perinatal HIV Infection
Linda A. DiMeglio,Jiajia Wang,George K. Siberry,Tracie L. Miller,Mitchell E. Geffner,Rohan Hazra,William Borkowsky,Janet S Chen,Laurie B. Dooley,Kunjal Patel,Russell B. Van Dyke,Roger A. Fielding,Yared Gurmu,Denise L. Jacobson +13 more
TL;DR: Rates of low BMD in HIV+ children were greater than expected based on normal population distributions, partially explained by delays in growth.
Journal ArticleDOI
Metformin Use and Clinical Outcomes Among Patients With Diabetes Mellitus With or Without Heart Failure or Kidney Dysfunction: Observations From the SAVOR-TIMI 53 Trial.
Brian A. Bergmark,Deepak L. Bhatt,Darren K. McGuire,Avivit Cahn,Ofri Mosenzon,Ph. Gabriel Steg,KyungAh Im,Estella Kanevsky,Yared Gurmu,Itamar Raz,Eugene Braunwald,Benjamin M. Scirica,Investigators +12 more
TL;DR: In a cohort of 12,156 patients with T2DM and high CV risk, metformin use was associated with lower rates of all-cause mortality, including after adjustment for clinical variables and biomarkers, but notLower rates of the composite endpoint of CV death, MI, or ischemic stroke.