Y
Yashodeep Shinde
Publications - 3
Citations - 55
Yashodeep Shinde is an academic researcher. The author has contributed to research in topics: Osimertinib & T790M. The author has an hindex of 1, co-authored 3 publications receiving 7 citations.
Papers
More filters
Journal ArticleDOI
Optimizing Bedaquiline for cardiotoxicity by structure based virtual screening, DFT analysis and molecular dynamic simulation studies to identify selective MDR-TB inhibitors.
TL;DR: In this article, a structure-based virtual screening approach was used to address the toxicity problems associated with Bedaquiline, and the results showed that CID15947587 could be a useful template for further optimizing the MDR-TB inhibitor.
Journal ArticleDOI
Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer.
Matin Shaikh,Yashodeep Shinde,Rahul Pawara,Malleshappa N. Noolvi,Sanjay J. Surana,Iqrar Ahmad,Harun M. Patel +6 more
TL;DR: The pyrimidine core-containing compound Osimertinib is the only EGFR-TKI from the third generation that has been approved by the U.S. Food and Drug Administration to target threonine 790 methionine (T790M) resistance while sparing the wild-type epidermal growth factor receptor (WT EGFR) as discussed by the authors.
Journal ArticleDOI
The Mur Enzymes Chink in the Armour of Mycobacterium tuberculosis cell wall.
TL;DR: In this paper, the authors have discussed the recent advances in medicinal chemistry of Mtb Mur enzymes and their inhibitors, offering attractive multi-targeted strategies to combat the problem of drug-resistant in M. tuberculosis.