Yasuaki Ogawa

TL;DR: The kinetic analysis demonstrated that the RES uptake rate was almost the same among the liposomes, while the systemic degradation rate became larger as the content of DSPC decreased and the Kdeg for each type of liposome corresponded with the systemic CDDP release rate.

TL;DR: The present ELISA is so rapid, sensitive and selective for TAK-778 that it could be conveniently used in a clinical field for the determination of many serum specimens.

TL;DR: A water-soluble composition which comprises a pharmacologically active polypeptide, erythropoietin, secreted by an animal body or its derivative or a chemically synthesized pharmacological active substance, such as hyaluronic acid or its nontoxic salt, and injectable into body fluids without showing any substantial pharmacological activity brings about a prolonged action in vivo of a pharmaceutical active substance as mentioned in this paper.

TL;DR: The biological properties of an immune complex composed of recombinant interleukin-2 and an F(ab')2 fragment of a monoclonal antibody against rIL-2 in mice for the induction of killer cells and anti-tumor activity are investigated, as well as the pharmacokinetic properties of the immune complex injected subcutaneously into mice.

TL;DR: The result from the gel electrophoresis employing Western blotting suggests that ICAM-1 circulates in at least two molecular forms with molecular masses of about 85 and 130 kDa and with different reactivities to WIS2-11 and WIS5-85.