Yasuhiro Ueno

TL;DR: Blood acetaldehyde levels scarcely increased in the subjects homozygous for ALDH2*1, regardless of their ADH2 genotype, and the values of Widmark's beta 60 and ethanol elimination rate showed significant differences among the three ALDH 2 genotypes, and in decreasing order the values were ALDH1/*1, ALDH*1/*2, AL DH2*2*/2, however, no significant differences were seen among the ADH1 genotypes.

TL;DR: By a complex series of mechanisms, alcohol adversely affects skeletal muscle, and there are important metabolic consequences, by virtue of the fact that skeletal muscle is 40% of body mass and an important contributor to whole‐body protein turnover.

TL;DR: This study is the first to report the occurrence of facial flushing and raised blood acetaldehyde concentration among Japanese alcoholics, and a great difference in response to alcohol between alcoholics and healthy men.

TL;DR: A simple and rapid method for the simultaneous determination of phosphorus-containing amino acid herbicides and their major metabolites, aminomethylphosphonic acid (AMPA) and 3-methylphosphinicopropionic acid (MPPA), in human serum is developed.

TL;DR: Investigation of influence of genetic polymorphism at the ADH2 and ALDH2 loci on ethanol elimination and blood acetaldehyde level was studied in healthy subjects and there were no significant differences in the values among the ADh2 genotypes.