Y
Ye Yuan
Researcher at Hubei University of Medicine
Publications - 4
Citations - 64
Ye Yuan is an academic researcher from Hubei University of Medicine. The author has contributed to research in topics: Cellular differentiation & Small hairpin RNA. The author has an hindex of 3, co-authored 3 publications receiving 33 citations.
Papers
More filters
Journal ArticleDOI
Continuous exposure of isoprenaline inhibits myoblast differentiation and fusion through PKA/ERK1/2-FOXO1 signaling pathway
Shao-juan Chen,Jing Yue,Jing-Xuan Zhang,Miao Jiang,Tu-qiang Hu,Wei-dong Leng,Li Xiang,Xin-yuan Li,Lei Zhang,Fei Zheng,Ye Yuan,Linyun Guo,Ya-mu Pan,Yu-wen Yan,Jia-Ning Wang,Shi-You Chen,Jun-Ming Tang +16 more
TL;DR: Continuous exposure of ISO impedes satellite cell differentiation and myoblast fusion, at least in part, through PKA-ERK1/2-FOXO1 signaling pathways, which were associated with the reduced β2-AdR and increased β1- adrenergic receptors levels.
Journal ArticleDOI
S100B is required for maintaining an intermediate state with double-positive Sca-1+ progenitor and vascular smooth muscle cells during neointimal formation
Yan Wu,Xin Liu,Ling-Yun Guo,Lei Zhang,Fei Zheng,Shan Li,Xing-Yuan Li,Ye Yuan,Yu Liu,Yu-wen Yan,Shi-You Chen,Jia-Ning Wang,Jin-xuan Zhang,Jun-Ming Tang +13 more
TL;DR: S100B triggered neointimal formation in rat injured arteries by maintaining the intermediate state of double-positive Sca-1+ progenitor and VSMCs, which were associated with direct activation of RAGE by S100B and indirect induction of SDF-1α by activating PI3K/AKT and NF-κB.
Journal ArticleDOI
KPC1 alleviates hypoxia/reoxygenation-induced apoptosis in rat cardiomyocyte cells though BAX degradation.
Ye Yuan,Yong‐yi Wang,Xin Liu,Bin Luo,Lei Zhang,Fei Zheng,Xing-Yuan Li,Ling-Yun Guo,Lu Wang,Miao Jiang,Ya-mu Pan,Yu-wen Yan,Jian-Ye Yang,Shi-You Chen,Jia-Ning Wang,Jun-Ming Tang +15 more
TL;DR: KPC1 prevented basal and apoptotic stress‐induced Bax translocation to mitochondria, suggesting that Bax can be a novel target for the antiapoptotic effects of KPC1 on I/R‐induced cardiomyocyte apoptosis and render mechanistic penetration into at least a subset of the mitochondrial effects of kPC1.
Journal ArticleDOI
Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth
Ying Jin,Yamu Pan,Sijia Zheng,Yao Liu,Jie Xu,Yaqin Peng,Zemei Zhang,Yadong Wang,Yulian Xiong,Lei Xu,Kaiyu Mu,Suwen Chen,Fei Zheng,Ye Yuan,Jian Fu +14 more
TL;DR: This article showed that EGLN3-catalyzed hydroxylation antagonizes CMA-lysosome pathway degradation of Erk3 and showed that inactivation of EGLn3 in malignant and stromal cells suppresses tumor by orchestrating reciprocal interplays between cancer cells and the tumor microenvironment.