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Yefeng Cai
Researcher at Guangzhou University of Chinese Medicine
Publications - 27
Citations - 1095
Yefeng Cai is an academic researcher from Guangzhou University of Chinese Medicine. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 13, co-authored 20 publications receiving 867 citations.
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Journal ArticleDOI
Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.
Yong Huo,Jianping Li,Xianhui Qin,Xianhui Qin,Yining Huang,Xiaobin Wang,Rebecca F. Gottesman,Rebecca F. Gottesman,Genfu Tang,Binyan Wang,Binyan Wang,Dafang Chen,Mingli He,Jia Fu,Yefeng Cai,Xiuli Shi,Yan Zhang,Yimin Cui,Ningling Sun,Xiaoying Li,Xiaoshu Cheng,Jian’an Wang,Xinchun Yang,Tianlun Yang,Chuanshi Xiao,Gang Zhao,Qiang Dong,Dingliang Zhu,Xian Wang,Junbo Ge,Lianyou Zhao,Dayi Hu,Lisheng Liu,Fan Fan Hou +33 more
TL;DR: Among adults with hypertension in China without a history of stroke or MI, the combined use of enalapril and folic acid, compared with en alapril alone, significantly reduced the risk of first stroke.
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Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Jing Nie,Liling Xie,Bo-xin Zhao,Youbao Li,Bingbing Qiu,Fengxin Zhu,Guo-feng Li,Mingli He,Wang Yu,Binyan Wang,Side Liu,Hao Zhang,Huiyuan Guo,Yefeng Cai,Yong Huo,Fan Fan Hou,Xiping Xu,Xianhui Qin +17 more
TL;DR: Higher TMAO levels were associated with increased risk of first stroke in hypertensive patients, and calls for a carefully designed clinical trial to further evaluate the role of higher TmaO levels on outcomes in hypertension patients.
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Homocysteine and Stroke Risk: Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention
Min Zhao,Xiaobin Wang,Mingli He,Xianhui Qin,Genfu Tang,Yong Huo,Jianping Li,Jia Fu,Xiao Huang,Xiaoshu Cheng,Binyan Wang,Fan Fan Hou,Ningling Sun,Yefeng Cai +13 more
TL;DR: In Chinese hypertensive patients, the effect of homocysteine on the first stroke was significantly modified by the methylenetetrahydrofolate reductase C677T genotype and folic acid supplementation, which may help to more precisely predict stroke risk and develop folic Acid interventions tailored to individual genetic background and nutritional status.
Journal ArticleDOI
Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
Xianhui Qin,Jianping Li,J. David Spence,Yan Zhang,Youbao Li,Xiaobin Wang,Binyan Wang,Ningling Sun,Fang Chen,Jingxuan Guo,Delu Yin,Liming Sun,Genfu Tang,Mingli He,Jia Fu,Yefeng Cai,Xiuli Shi,Ping Ye,Hong Chen,Shuiping Zhao,Mao Chen,Chuanyu Gao,Xiangqing Kong,Fan Fan Hou,Yining Huang,Yong Huo +25 more
TL;DR: Elevated total cholesterol levels may modify the benefits of folic acid therapy on first stroke and reduce the risk of first stroke associated with elevated total cholesterol by 31% among hypertensive adults without a history of major cardiovascular diseases.
Journal ArticleDOI
Prevalence of hyperhomocysteinaemia and its major determinants in rural Chinese hypertensive patients aged 45-75 years.
Yu Wang,Xiaoying Li,Xianhui Qin,Yefeng Cai,Mingli He,Liming Sun,Jianping Li,Yan Zhang,Genfu Tang,Binyan Wang,Ningling Sun,Xin Xu,Lisheng Liu,Xiping Xu,Yong Huo +14 more
TL;DR: There was a high prevalence of hyperhomocysteinaemia in Chinese hypertensive adults, particularly in the inlanders, who may benefit greatly from tHcy-lowering strategies, such as folic acid supplementation and lifestyle change.