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Yeu Su
Researcher at National Yang-Ming University
Publications - 20
Citations - 790
Yeu Su is an academic researcher from National Yang-Ming University. The author has contributed to research in topics: Apoptosis & Mesenchymal stem cell. The author has an hindex of 14, co-authored 20 publications receiving 753 citations. Previous affiliations of Yeu Su include Taipei Veterans General Hospital.
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Journal ArticleDOI
Overexpression of the thymosin β-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma
Wei Shu Wang,Wei Shu Wang,Po Min Chen,Hung Liang Hsiao,Huann Sheng Wang,Wen Yih Liang,Yeu Su +6 more
TL;DR: The results suggest that upregulation of Tβ-4, by promoting the disruption of cell–cell adhesion and a consequential activation of the β-catenin signaling, could be a key event in the acquisition of growth advantages as well as invasive phenotypes in human colorectal carcinomas.
Journal ArticleDOI
Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 co-expressing mesenchymal stem cells.
TL;DR: To the authors' knowledge, this is the first report to show unequivocally the feasibility of ameliorating glucocorticoid‐induced osteoporosis by systemic transplantation of genetically manipulated MSCs.
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Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma
TL;DR: The results suggest that Fas downregulation and a consequential increased resistance to FasL-triggered apoptosis resulting from upregulated MMP-7 in colorectal cancer cells could be a key mechanism for their escape from the immune surveillance, thereby predicting a poor survival in CRC patients.
Journal ArticleDOI
Overexpression of the thymosin β-4 gene is associated with malignant progression of SW480 colon cancer cells
TL;DR: The data suggest that the drastic growth property and motility changes of the SW480 cells overexpressing Tβ-4 gene are due mainly to a deregulated cell–cell adhesion arisen from the downregulation of E-cadherin, plus uncontrolled cell proliferation owing to the upregulation of β-catenin.
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c‐Jun N‐terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104
TL;DR: It is shown that JNK1 is activated by BMP2 in multipotent C2C12 and preosteoblastic MC3T3‐E1 cell lines, and Runx2 is required for J NK1‐mediated inhibition of osteoblastic differentiation, and identified Ser104 of Runx 2 is the site phosphorylated by JNK 1 upon BMP1 stimulation.