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Yewei Zhang
Researcher at Guiyang Medical University
Publications - 20
Citations - 138
Yewei Zhang is an academic researcher from Guiyang Medical University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 2, co-authored 3 publications receiving 26 citations.
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Journal ArticleDOI
Positive feedback loop of FAM83A/PI3K/AKT/c-Jun induces migration, invasion and metastasis in hepatocellular carcinoma
Chen Liu,Xuemei Peng,Yonghao Li,Shu Liu,Rentao Hou,Yewei Zhang,Shi Zuo,Zhan Liu,Rongcheng Luo,Libo Li,Weiyi Fang +10 more
TL;DR: FAM83A, as a cancer-metastasis promoter, accelerates migration, invasion and metastasis by activating the PI3K/AKT/c-JUN pathway and inducing its self-expression via feedback, thus forming a FAM83A/PI3K-AKT-c- JUN positive-feedback loop to activate EMT signaling and finally promote HCC migration, invaded and metastases.
Journal ArticleDOI
Molecular Characteristics, Clinical Significance, and Cancer Immune Interactions of Angiogenesis-Associated Genes in Gastric Cancer
TL;DR: A prognostic AAG signature is identified for GC patients that may contribute to clarifying the characteristics of TME and enable the exploration of more potent immunotherapy strategies.
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MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis.
TL;DR: It is demonstrated that MAP2K4 has the potential to serve as an oncogene in breast cancer and it activates the phosphorylated PI3K/AKT signaling pathway to activate downstream cycle-associated proteins and EMT signals while interacting with Vimentin to promote breast cancer cells proliferation, migration, and invasion.
Journal ArticleDOI
Advances of cancer-associated fibroblasts in liver cancer
Hao Peng,Erwei Zhu,Yewei Zhang +2 more
TL;DR: In this article , a review of cancer-associated fibroblasts (CAFs) in liver cancer is presented, including their cell origins, chemoresistance, tumor stemness induction, tumor immune microenvironment formation, and the role of tumor cells on CAFs.
Journal ArticleDOI
ENKUR expression induced by chemically synthesized cinobufotalin suppresses malignant activities of hepatocellular carcinoma by modulating β-catenin/c-Jun/MYH9/USP7/c-Myc axis
Rentao Hou,Yonghao Li,Xiao Shan Luo,Wan Zhang,Huiling Yang,Yewei Zhang,Jiahao Liu,Shaohua Liu,Siyuan Han,Chen Liu,Yun Hu Huang,Zhen Liu,Aimin Li,Weiyi Fang +13 more
TL;DR: Findings show that ENKUR induced by CB antagonizes β-catenin/c-Jun/MYH9/USP7 pathway, thus increasing c-Myc ubiquitin degradation and finally suppressing cell cycle and EMT signals.