Yi Hu

TL;DR: Pretreatment LDH may serve as a predictive biomarker for advanced NSCLC patients treated with ICIs and was significantly correlated with shorter PFS and OS.

TL;DR: The risk of pneumonitis induced by anti‐ PD‐1 mAbs is associated with prior thoracic radiotherapy, prior lung disease, and combination therapy, and Clinicians should monitor these features in patients receiving anti‐PD‐1 therapy to optimize clinical safety and efficacy.

TL;DR: Camrelizumab plus apatinib showed potential antitumor activity in both chemotherapy-sensitive and chemotherapy-resistant ED-SCLC patients who had failed platinum-based chemotherapy with acceptable toxicity profile, and this phase 2 data warrant further clinical studies of camrelizUMab plus Apatinib in SCLC.

TL;DR: It is found that protein tyrosine kinase 2 (PTK2) expression correlated with liver CSC marker expression, overall survival, and recurrence-free survival in HCC patients, and PTK2 expression was negatively correlated with its level of promoter methylation.

TL;DR: SOX10 is thus a commonly inactivated tumor suppressor that antagonizes Wnt/β-catenin signaling in cancer cells from different digestive tissues and transrepresses its downstream target genes via its own DNA-binding property.