Exemplary method, apparatus and arrangement can be provided for obtaining information associated with a sample such as a portion of an anatomical structure. The information can be generated using first data, which can be based on a signal obtained from a location on the sample, and second data, where the second data can be obtained by combining a second signal received from the sample with a third reference signal. An image of a portion of the sample can also be generated based on the information. For example, the first data can be associated with spectral encoding microscopy data, and the second data can be associated with optical coherence tomography data.

Method and apparatus for optical imaging via spectral encoding

A method for obtaining a tomographic image of a fundus by optical coherence tomography includes the steps of setting a line, based on which the fundus tomographic image is to be obtained, on a first front image of the fundus, the first front image being a still image, establishing a positional correspondence between a second front image of the fundus and the first front image by matching the first and second front images, specifying a line on the second front image based on positional information on the line set on the first front image, and the established positional correspondence, and obtaining the fundus tomographic image that corresponds to the lines on the first and second front images by scanning measurement light with the use of an optical scanner provided to an interference optical system.

Ophthalmic photographing apparatus

An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.

Method and apparatus for imaging of vessel segments

Method and apparatus according to an exemplary embodiment of the present invention can be provided. For example, first data associated with a first signal received from at least one region of at least one sample can be provided based on a first modality, and second data associated with a second signal received from the at least one sample can be provided based on a second modality which is different from the first modality. Third data associated with a reference can be received. Further data can be generated based on the first, second and third data. In addition, third data associated with a second signal received from the at least one sample can be obtained. Each of the third data can be based on a further modality which is different from the first modality and the second modality, and the further data can be further determined based on the third data. Further, the first modality can be a spectral-encoded modality, and the second modality can be a non-spectral-encoding modality.

Arrangements and methods for providing multimodality microscopic imaging of one or more biological structures

Imaging system and related techniques

PROBLEM TO BE SOLVED: To verify fine structures including birefringence distribution which has not been acquired by a conventional OCT (optical coherence tomography) measurement in the measurement of cross-sectional structures of biosamples including the birefringence distribution such as fish bones and human skin. SOLUTION: The sate of reference light and the state of object light are each selectively regulated into any one of the four ways of horizontal linear polarized light, vertical linearly polarized light, 45° linearly polarized light, and right-handed circularly polarized light. Each state of polarized light is combined by a beam splitter 10 into sixteen-way combinations of four by four, and is passed through a spectroscope having a diffraction grating 20 and lenses. Its interference fringes are photographed by a CCD camera 22 to acquire sixteen coherence tomographic images. By determining each element of the Mueller matrix capable of displaying the polarization characteristics of the sample from the sixteen coherence tomographic images, the polarization information inside the sample is measured. COPYRIGHT: (C)2004,JPO

Polarization-sensitive optical spectral interferometric coherence tomography apparatus and measuring method for polarization information inside sample by the same

PROBLEM TO BE SOLVED: To use a program as useful means for computer diagnosis by nonlinearly correcting data measured by a PS-OCT, improving the quantitative analysis ability of the PS-OCT and enabling an accurate quantitative diagnosis including a disease stage of an affected region.SOLUTION: Even when retardation in a PS-OCT 1 contains an error and becomes noise and the distribution thereof is neither a normal distribution nor symmetrical about a true value, a systematic error is removed by converting measured data using a distribution conversion function obtained by analyzing the characteristics of the noise by Monte Carlo simulation to thereby estimate the true value buried in the noise and correct images taken by the PS-OCT 1 to make them clearer.

Program to correct data measured by ps-oct and ps-oct system comprising the program

L'objectif de la presente invention vise a reduire la gigue entre le balayage de la longueur d'onde d'une source laser et le moment auquel des donnees sont recueillies par un detecteur de lumiere sous la forme d'un signal d'interferences spectrales; de plus, il vise a stabiliser la phase du tomographe sans avoir a utiliser un materiel couteux et complexe supplementaire. La lumiere est emise depuis une source laser a balayage de longueur d'onde SS-OCT (2) et est divisee en faisceaux. La lumiere de reference reflechie a partir d'un miroir de reference (8) fixe et l'objet lumineux reflechi par un objet (6) qui doivent etre mesures se superposent. Un ordinateur (16) produit une image tomographique sur la base d'un signal d'interferences spectrales localise par un detecteur de lumiere (15). L'ordinateur est amene a fonctionner de sorte qu'une correction de base est effectuee a l'aide d'un premier moyen de correction et une correction plus detaillee est effectuee par un second moyen de correction, stabilisant ainsi la phase de la SS-OCT.

Tomographe à cohérence optique en swept source et procédé de stabilisation de la phase correspondante

The present invention achieves Jones matrix OCT having improved image stability and image quality and an improved image depth region Light from a wavelength scanning light source (6) is divided into two light paths A reference arm (12) is provided in one of the light paths, and a probe arm (13) that generates object light by irradiating light onto an object under measurement and causing the light to be reflected is provided in the other light path The probe arm (13) is provided with a polarization delay unit (21) for linearly polarizing the light, subsequently dividing the light into an S-wave component and a P-wave component, passing the S-wave component and P-wave component through light paths having different light path lengths, and superimposing the components Photodetectors (68, 70) detect different spectral interference light in the depth direction of the object under measurement corresponding to the S-wave component and P-wave component of the spectral interference light corresponding to a vertically polarized component and a horizontally polarized component and obtain four spectral interference signals

伊藤雅英

Papers

Polarization-sensitive optical spectral interferometric coherence tomography apparatus and measuring method for polarization information inside sample by the same

Program to correct data measured by ps-oct and ps-oct system comprising the program

Tomographe à cohérence optique en swept source et procédé de stabilisation de la phase correspondante

Jones matrix oct system and program for carrying out image processing on measured data obtained by said oct

伊藤 雅英

Papers

Polarization-sensitive optical spectral interferometric coherence tomography apparatus and measuring method for polarization information inside sample by the same

Program to correct data measured by ps-oct and ps-oct system comprising the program

Tomographe à cohérence optique en swept source et procédé de stabilisation de la phase correspondante

Jones matrix oct system and program for carrying out image processing on measured data obtained by said oct

伊藤雅英