Showing papers by "Yibin Kang published in 2023"
24 citations
TL;DR: In this paper , the authors discuss the mechanisms governing organ-specific metastasis in breast cancer, focusing on the intricate interactions between metastatic cells and specific niche cells within a secondary organ, and the remarkable adaptations of both compartments that cooperatively support cancer growth.
Abstract: Cancer metastasis, or the development of secondary tumors in distant tissues, accounts for the vast majority of fatalities in patients with breast cancer. Breast cancer cells show a striking proclivity to metastasize to distinct organs, specifically the lung, liver, bone, and brain, where they face unique environmental pressures and a wide variety of tissue-resident cells that together create a strong barrier for tumor survival and growth. As a consequence, successful metastatic colonization is critically dependent on reciprocal cross talk between cancer cells and host cells within the target organ, a relationship that shapes the formation of a tumor-supportive microenvironment. Here, we discuss the mechanisms governing organ-specific metastasis in breast cancer, focusing on the intricate interactions between metastatic cells and specific niche cells within a secondary organ, and the remarkable adaptations of both compartments that cooperatively support cancer growth. More broadly, we aim to provide a framework for the microenvironmental prerequisites within each distinct metastatic site for successful breast cancer metastatic seeding and outgrowth.
TL;DR: The Altmetric Attention Score as discussed by the authors is a quantitative measure of the attention that a research article has received online, which is calculated using the Alt-Metric attention score metric.
Abstract: ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to “Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction”Hailing ChenHailing ChenMore by Hailing Chen, Meimiao ZhanMeimiao ZhanMore by Meimiao Zhan, Jianbo LiuJianbo LiuMore by Jianbo Liu, Zhihong LiuZhihong LiuMore by Zhihong Liu, Minhong ShenMinhong ShenMore by Minhong Shen, Fenfang YangFenfang YangMore by Fenfang Yang, Yibin Kang*Yibin KangMore by Yibin Kang, Feng Yin*Feng YinMore by Feng Yin, and Zigang Li*Zigang LiMore by Zigang Lihttps://orcid.org/0000-0002-3630-8520Cite this: J. Med. Chem. 2023, 66, 11, 7668Publication Date (Web):May 25, 2023Publication History Received18 May 2023Published online25 May 2023Published inissue 8 June 2023https://doi.org/10.1021/acs.jmedchem.3c00892Copyright © 2023 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views319Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (673 KB) Get e-Alertsclose Get e-Alerts