Y
Yichen Hu
Publications - 2
Citations - 80
Yichen Hu is an academic researcher. The author has contributed to research in topics: Intracellular pH & Chemistry. The author has an hindex of 1, co-authored 2 publications receiving 20 citations.
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Genipin-crosslinked human serum albumin coating using a tannic acid layer for enhanced oral administration of curcumin in the treatment of ulcerative colitis
Ruifeng Luo,Meisi Lin,Chen Zhang,Jin-Feng Shi,Siyuan Zhang,Qiyan Chen,Yichen Hu,Minyue Zhang,Jinming Zhang,Fei Gao +9 more
TL;DR: An oral food-grade nanocarrier composed of tannic acid (TA)-coated, Genipin (Gnp)-crosslinked human serum albumin (HSA) to encapsulate CUR (TA/CUR-NPs) significantly alleviated colitis symptoms in DSS-treated mice when compared with controls by inhibiting the TLR4-linked NF-κB signaling pathway.
Journal ArticleDOI
pH/ROS dual-sensitive and chondroitin sulfate wrapped poly (β-amino ester)-SA-PAPE copolymer nanoparticles for macrophage-targeted oral therapy for ulcerative colitis.
Haiting Xu,Ruifeng Luo,Lingling Dong,Xiulan Pu,Qiyan Chen,Naijing Ye,Shanshan Qi,Xiaoqin Han,Wenbiao Nie,Chaomei Fu,Yichen Hu,Jinming Zhang,Fei Gao +12 more
TL;DR: An oral nanoparticle (NPs) encapsulated in chitosan/alginate hydrogel (CA-Gel) with dual-sensitive in pH and reactive oxygen species (ROS) was developed to load curcumin (CUR) based on the intracellular-specific characteristics of macrophages as discussed by the authors.