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Yijing Shen
Researcher at Genentech
Publications - 4
Citations - 2581
Yijing Shen is an academic researcher from Genentech. The author has contributed to research in topics: Atezolizumab & Hazard ratio. The author has an hindex of 3, co-authored 4 publications receiving 1720 citations.
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Journal ArticleDOI
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
Mark A. Socinski,Robert M. Jotte,Federico Cappuzzo,Francisco Orlandi,Daniil Stroyakovskiy,Naoyuki Nogami,Delvys Rodriguez-Abreu,Denis Moro-Sibilot,Christian A. Thomas,Fabrice Barlesi,Gene Grant Finley,Claudia Kelsch,Anthony Lee,Shelley Coleman,Yu Deng,Yijing Shen,Marcin Kowanetz,Ariel Lopez-Chavez,Alan Sandler,Martin Reck +19 more
TL;DR: The addition of atezolizumab to bevacIZumab plus chemotherapy significantly improved progression‐free survival and overall survival among patients with metastatic nonsquamous NSCLC, regardless of PD‐L1 expression and EGFR or ALK genetic alteration status.
Journal ArticleDOI
Overall survival (OS) analysis of IMpower150, a randomized Ph 3 study of atezolizumab (atezo) + chemotherapy (chemo) ± bevacizumab (bev) vs chemo + bev in 1L nonsquamous (NSQ) NSCLC.
Mark A. Socinski,Robert M. Jotte,Federico Cappuzzo,Francisco Orlandi,Daniil Stroyakovskiy,Naoyuki Nogami,Delvys Rodriguez-Abreu,Denis Moro-Sibilot,Christian A. Thomas,Fabrice Barlesi,Gene Grant Finley,Claudia Kelsch,Anthony Lee,Shelley Coleman,Yijing Shen,Marcin Kowanetz,Ariel Lopez-Chavez,Alan Sandler,Martin Reck +18 more
TL;DR: The IMpower150 interim OS results show PFS benefit was observed with atezo + CP + bev vs CP +Bev regardless of PD-L1 expression, and bev may enhance ateze efficacy by inhibiting VEGF immunosuppression and promoting T-cell tumor infiltration.
Journal ArticleDOI
LBA1_PRPrimary PFS and safety analyses of a randomized phase III study of carboplatin + paclitaxel +/− bevacizumab, with or without atezolizumab in 1L non-squamous metastatic nsclc (IMPOWER150)
Martin Reck,Mark A. Socinski,Frederico Cappuzzo,Francisco Orlandi,D Stroyakovskii,Naoyuki Nogami,Delvys Rodriguez-Abreu,Denis Moro-Sibilot,Christian A. Thomas,Fabrice Barlesi,Gene Grant Finley,Claudia Kelsch,Anthony Lee,Shelley Coleman,Yijing Shen,Marcin Kowanetz,Ariel Lopez-Chavez,Alan Sandler,Robert M. Jotte +18 more
Journal ArticleDOI
356TiPPhase III clinical trials of atezolizumab in combination with chemotherapy in chemotherapy-naive patients with advanced NSCLC
Tony Mok,Frederico Cappuzzo,Robert M. Jotte,Martin Reck,Vassiliki A. Papadimitrakopoulou,Alan Sandler,Daniel Waterkamp,Wendy Verret,Yijing Shen,Mark A. Socinski +9 more