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Ying Cheng

Researcher at Fourth Military Medical University

Publications -  29
Citations -  702

Ying Cheng is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 20 publications receiving 438 citations.

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Comparision of piceid and resveratrol in antioxidation and antiproliferation activities in vitro.

TL;DR: Piceid exhibited higher scavenging activity against hydroxyl radicals than resveratrol in vitro, and showed a significant protective effect against H2O2-induced cell damage.
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Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats

TL;DR: Mitochondria-targeted nanoparticles (CsA@PLGA-PEG-SS31) exhibited significant cardioprotective effects against MI/RI in rats hearts through protecting mitochondrial integrity, decreasing apoptosis of cardiomyocytes and myocardial infract area and offered a promising therapeutic method for patients with acute myocardIAL infarction.
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Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.

TL;DR: Doxorubicin and resveratrol co-encapsulated in a modified PLGA nanoparticle (NPS) could overcome the DOX resistance and had the potential in the treatment of DOX-resistant breast cancer.
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The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle.

TL;DR: In vivo experiments indicated that siPLK1 selectively accumulated in the brain tissue, and markedly reduced tumor volume and prolonged the survival time of GBM-bearing mice after Tf-PEG-PLL/MNP@siPLK 1 was injected to GBM -bearing mice via tail vein.
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Mitochondria-targeted antioxidant delivery for precise treatment of myocardial ischemia-reperfusion injury through a multistage continuous targeted strategy.

TL;DR: A smart dual-shell polymeric nanoparticle, MCTD-NPs, is reported, which utilizes multistage continuous targeted strategy to deliver reactive oxygen species scavenger specifically to mitochondria of ischemic cardiomyocytes upon systemic administration to treat MI/RI.