Yong Du

TL;DR: The present study demonstrates that ultraviolet photolysis of CH2I2 at low concentration leads to efficient dehalogenation and release of multiple strong acid (HI) leaving groups and suggests thatCH2I-I is the species that reacts with water to produce the CH2(OH)2 and 2HI products seen in the photochemistry experiments.

TL;DR: Vibrational spectroscopic techniques used in solid-state pharmaceutical analysis include mid-infrared, Raman and terahertz spectroscopy, which are focused on the polymorphism and cocrystallization of APIs in pharmaceutical fields.

TL;DR: In this paper, the vibrational properties of the cocrystal of nitrofurantoin and 4-aminobenzoic acid were characterized using Raman and terahertz spectroscopic techniques.

TL;DR: Complete active-space self-consistent field (CASSCF) calculations with a (14,11) active space and density functional theory calculations followed by Car-Parrinello molecular dynamic simulations are reported for the p-hydroxyphenacyl acetate, diethyl phosphate, and diphenyl phosphate phototrigger compounds to reveal the role of water in promoting the photodeprotection and subsequent rearrangement reactions.

TL;DR: In this paper, femtosecond transient absorption (fs-TA), resonance Raman (RR), and nanosecond time-resolved resonance Rambus (ns-TR3) spectroscopic methods were used to better elucidate the possible photochemical reaction mechanism of suprofen in several different solvents.