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Yoshimitsu Tanaka
Researcher at Osaka University
Publications - 11
Citations - 485
Yoshimitsu Tanaka is an academic researcher from Osaka University. The author has contributed to research in topics: Adiponectin & White adipose tissue. The author has an hindex of 8, co-authored 11 publications receiving 290 citations.
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Journal ArticleDOI
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release
Yoshinari Obata,Shunbun Kita,Yoshihisa Koyama,Shiro Fukuda,Hiroaki Takeda,Masatomo Takahashi,Yuya Fujishima,Hirofumi Nagao,Shigeki Masuda,Yoshimitsu Tanaka,Yuto Nakamura,Hitoshi Nishizawa,Tohru Funahashi,Barbara Ranscht,Yoshihiro Izumi,Takeshi Bamba,Eiichiro Fukusaki,Rikinari Hanayama,Shoichi Shimada,Norikazu Maeda,Iichiro Shimomura +20 more
TL;DR: It is demonstrated that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides, in mice treated with angiotensin II.
Journal ArticleDOI
Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice.
Yuto Nakamura,Shunbun Kita,Yoshimitsu Tanaka,Shiro Fukuda,Yoshinari Obata,Tomonori Okita,Hiroyuki Nishida,Yuki Takahashi,Yusuke Kawachi,Yuri Tsugawa-Shimizu,Yuya Fujishima,Hitoshi Nishizawa,Yoshinobu Takakura,Shigeru Miyagawa,Yoshiki Sawa,Norikazu Maeda,Iichiro Shimomura +16 more
TL;DR: It is reported that the cardioprotective properties of intravenously injected MSCs in a mouse model of pressure-overload heart failure largely depend on circulating adiponectin, an adipocyte-secreted factor.
Journal ArticleDOI
Adiponectin promotes muscle regeneration through binding to T-cadherin.
Yoshimitsu Tanaka,Shunbun Kita,Hitoshi Nishizawa,Shiro Fukuda,Yuya Fujishima,Yoshinari Obata,Hirofumi Nagao,Shigeki Masuda,Yuto Nakamura,Yuri Shimizu,Ryohei Mineo,Tomoaki Natsukawa,Tohru Funahashi,Barbara Ranscht,So-ichiro Fukada,Norikazu Maeda,Iichiro Shimomura +16 more
TL;DR: It is demonstrated that adiponectin stimulates muscle regeneration through T-cadherin, where intracellular accumulation and exosome-mediated process of adiponECTin may have some roles.
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Association of Epicardial, Visceral, and Subcutaneous Fat With Cardiometabolic Diseases.
Fumi Sato,Norikazu Maeda,Takayuki Yamada,Hideyuki Namazui,Shiro Fukuda,Tomoaki Natsukawa,Hirofumi Nagao,Jun Murai,Shigeki Masuda,Yoshimitsu Tanaka,Yoshinari Obata,Yuya Fujishima,Hitoshi Nishizawa,Tohru Funahashi,Iichiro Shimomura +14 more
TL;DR: Epicardial fat accumulation may be a risk for coronary atherosclerosis in subjects without visceral fat accumulation, and visceral fat is the strongest risk for cardiometabolic diseases among the 3 types of fat depot.
Journal ArticleDOI
Low muscle quality in Japanese type 2 diabetic patients with visceral fat accumulation
Jun Murai,Hitoshi Nishizawa,Akihito Otsuka,Shiro Fukuda,Yoshimitsu Tanaka,Hirofumi Nagao,Yasuna Sakai,Masahide Suzuki,Shinji Yokota,Hidetoshi Tada,Mayumi Doi,Yuya Fujishima,Shunbun Kita,Tohru Funahashi,Norikazu Maeda,Tadashi Nakamura,Iichiro Shimomura +16 more
TL;DR: T2DM patients with visceral fat accumulation had low muscle quality, and patients with high muscle quality were more affected with cardiovascular diseases.