Y
Yoshinori Nimura
Researcher at Shinshu University
Publications - 41
Citations - 1881
Yoshinori Nimura is an academic researcher from Shinshu University. The author has contributed to research in topics: Loss of heterozygosity & Gene. The author has an hindex of 21, co-authored 41 publications receiving 1835 citations.
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Journal ArticleDOI
Cloning and functional analysis of human p51, which structurally and functionally resembles p53
Motonobu Osada,Mai Ohba,Chikashi Kawahara,Chikashi Ishioka,Ryunosuke Kanamaru,Iyoko Katoh,Yoji Ikawa,Yoshinori Nimura,Akira Nakagawara,Masuo Obinata,Shuntaro Ikawa +10 more
TL;DR: In p53-deficient cells, p51A induced growth-suppression and apoptosis, and up-regulated p21waf-1 through p53 regulatory elements, and expression of p5I mRNA was found in a limited number of tissues, including skeletal muscle, placenta, mammary glands, prostate, trachea, thymus, salivary gland, uterus, heart and lung.
Journal Article
Mutation, allelotyping, and transcription analyses of the p73 gene in prostatic carcinoma
Hiroyuki Takahashi,Shingo Ichimiya,Yoshinori Nimura,Masatoshi Watanabe,Masakuni Furusato,Shin Wakui,Ryuichi Yatani,Shigeo Aizawa,Akira Nakagawara +8 more
TL;DR: The data suggest that the p73 gene is not playing an essential role, but expression of p73 may associate with tumor growth in prostatic carcinogenesis.
Journal ArticleDOI
p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent.
Shingo Ichimiya,Yoshinori Nimura,Hajime Kageyama,Naoyuki Takada,Masao Sunahara,Tomotane Shishikura,Yohko Nakamura,Shigeru Sakiyama,Naohiko Seki,Miki Ohira,Yasuhiko Kaneko,Frank McKeon,Daniel Caput,Akira Nakagawara +13 more
TL;DR: The results suggest that allelic loss of the p73 gene may be a later event in NBL tumorigenesis, however, p73 is infrequently mutated in primary NBLs and may hardly function as a tumor suppressor in a classic Knudson's manner.
Journal ArticleDOI
Cathepsin D Is a Potential Serum Marker for Poor Prognosis in Glioma Patients
Mieko E. Fukuda,Yasuo Iwadate,Toshio Machida,Takaki Hiwasa,Yoshinori Nimura,Yuichiro Nagai,Masaki Takiguchi,Hideki Tanzawa,Akira Yamaura,Naohiko Seki +9 more
TL;DR: The results collectively suggest that cathepsin D could be a potential serum marker for the prediction of aggressive nature of human gliomas.
Journal ArticleDOI
Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas.
M Sunahara,Shingo Ichimiya,Yoshinori Nimura,Naoyuki Takada,Shigeru Sakiyama,Yuji Sato,Satoru Todo,W Adachi,Jun Amano,Akira Nakagawara +9 more
TL;DR: The p73 gene was mapped at chromosome 1p36.3 which is a region frequently deleted in colorectal carcinoma (CRC) and other cancers including neuroblastoma as mentioned in this paper.