Yoshiro Matsuda

TL;DR: In this paper, les recents developpements dans la synthese heterocyclique a l'aide du dimethylacetal du nitrothiocetene (A), resultats des reactions de A avec les composes suivants: amines, composes a methylene actif, ylures d'azomethine, iminiums, enamines; reactions de derives substitues de A

Abstract: The reaction of various types of acetyl compounds with a ketene dithioacetal, methyl 2-cyano-3, 3-bis (methylthio) acrylate, in the presence of potassium hydroxide gave the corresponding 6-aryl-and 6-styryl-3-cyano-4-methylthio-2H-pyran-2-one derivatives. The methylthio group on the pyrone ring reacted readily with nucleophiles such as amines, active methylene compounds and methoxy anion to yield the corresponding displacement products in good yields.

TL;DR: In this article, the reaction of 1-ethoxycarbonylmethylpyridinium bromides 5a-k with nitro ketene dithioacetal, 1,1-bis-(methylthio)-2-nitroethylene (2), in the presence of triethylamine in ethanol gave the desired ethyl 2-methyl-thioindolizine-3-carboxylates 3a-K in good yields.

TL;DR: An effective and rapid one-step method of detecting and purifying fish plasma vitellogenin using a high-performance anion-exchange chromatography column, POROS-HQ, showed that in addition to a few females, some male fish synthesized vitelliogenin, suggesting that some chemicals or unknown factors with estrogenic activity have induced fish in the ocean to produce viteLLogenin.