Spin-labeling as a general method in studying antibody active site

Described are 2-cyanoacrylic acid esters (I) in which the groups are defined as follows: R?1 and R2? are hydrogen or a group with an isocyclic or heterocyclic ring system having at least one iso-aromatic or hetero-aromatic nucleus, whereby one of the groups R?1 and R2? must be different from hydrogen, n is from 2 to 10, X in the case when n = 2 is a group of the formula (II) in which m is from 2 to 8, X in the case when n > 2 is an n-hydric aliphatic or cycloaliphatic polyol group with 3 to 20 C-atoms, whereby the cycloaliphatic polyol group may include 1 to 2 hetero-atoms and the aliphatic polyol group may include up to 8 non-adjacent oxygen atoms, sulphur atoms, imino groups or C?1?-C4 alkylimino groups in the carbon chain. Compounds of the formula (I) are suitable for use as light-protection agents.

2-cyanoacrylic acid esters

The photo-stabilisation of polypropylene: a review

The effect of bis(2,2,6,6-Tetramethyl-1-oxyl-4-piperidinyl)succinate (Ro- 03-6061) on the survival parameters of V-79 Chinese hamster cells, irradiated under hypoxia, has been compared with related monofunctional nitroxyl compounds. The biradical is more effective in reducing the D$sub 0$ value than the three monoradical nitroxyls tested. It also removed the shoulder in asynchronous cell survival experiments, although this effect did not occur in the presence of oxygen. The shoulder for the survival curve for cells irradiated during late S phase was also reduced. Possible mechanisms for its actions are discussed in terms of the bifunctionality of the compound and the potential of such a sensitizer in radiotherapy is emphasized. (auth)

Polyfunctional radiosensitizers. I. Effects of a nitroxyl biradical on the survival of mammalian cells in vitro.

Mechanisms of antioxidant action: Behaviour of a hindered piperidine and related oxidation products during processing and photo-oxidation of polypropylene

1.

A method for the synthesis of a new water-soluble organic radical with a primary amino group has been developed.




2.

The splitting constant of the nitrogen triplet in the EPR spectrum of an aqueous solution of the radical is 16.2 oe.

A new individual free radical with a primary amino group

Inhibition of radical polymerization by nitroxide mono- and biradicals☆

1.

Nine new kinetically stable iminoxyl biradicals were synthesized.




2.

Using the EPR method, it was shown that the interaction of the unpaired electrons with the magnetic moments of the nitrogen nuclei in the free radicals is of an exchange character and changes with increase in the distance between the paramagnetic centers.

Yu.V. Kokhanov

Papers

A new individual free radical with a primary amino group

Inhibition of radical polymerization by nitroxide mono- and biradicals☆

New stable iminoxyl biradicals

Volatility and compatibility of stabilizers in polymers

Study of photo-stabilizer efficiencies for polymers by accelerated methods☆