Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

So far in this course we have dealt entirely with the evolution of characters that are controlled by simple Mendelian inheritance at a single locus. There are notes on the course website about gametic disequilibrium and how allele frequencies change at two loci simultaneously, but we didn’t discuss them. In every example we’ve considered we’ve imagined that we could understand something about evolution by examining the evolution of a single gene. That’s the domain of classical population genetics. For the next few weeks we’re going to be exploring a field that’s actually older than classical population genetics, although the approach we’ll be taking to it involves the use of population genetic machinery. If you know a little about the history of evolutionary biology, you may know that after the rediscovery of Mendel’s work in 1900 there was a heated debate between the “biometricians” (e.g., Galton and Pearson) and the “Mendelians” (e.g., de Vries, Correns, Bateson, and Morgan). Biometricians asserted that the really important variation in evolution didn’t follow Mendelian rules. Height, weight, skin color, and similar traits seemed to

Human biochemical genetics

BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

“Bioinformatics” 특집을 내면서

Malicious applications pose a threat to the security of the Android platform. The growing amount and diversity of these applications render conventional defenses largely ineffective and thus Android smartphones often remain unprotected from novel malware. In this paper, we propose DREBIN, a lightweight method for detection of Android malware that enables identifying malicious applications directly on the smartphone. As the limited resources impede monitoring applications at run-time, DREBIN performs a broad static analysis, gathering as many features of an application as possible. These features are embedded in a joint vector space, such that typical patterns indicative for malware can be automatically identified and used for explaining the decisions of our method. In an evaluation with 123,453 applications and 5,560 malware samples DREBIN outperforms several related approaches and detects 94% of the malware with few false alarms, where the explanations provided for each detection reveal relevant properties of the detected malware. On five popular smartphones, the method requires 10 seconds for an analysis on average, rendering it suitable for checking downloaded applications directly on the device.

/pdf/drebin-effective-and-explainable-detection-of-android-4kuv3sjqel.pdf

DREBIN: Effective and Explainable Detection of Android Malware in Your Pocket.

where A represents the magnetic vector potential, is an integral of the hydromagnetic equations. This -integral made it possible to formulate a variational principle for the force-free magnetic fields. The integral expresses the fact that motions cannot transform a given field in an entirely arbitrary different field, if the conductivity of the medium isconsidered infinite. In this paper we shall show that the full set of hydromagnetic equations admit five more integrals, besides the energy integral, if dissipative processes are absent. These integrals, as we shall presently verify, are I2 =fbHvdV, (2)

Proceedings of the National Academy of Sciences

One of Android's main defense mechanisms against malicious apps is a risk communication mechanism which, before a user installs an app, warns the user about the permissions the app requires, trusting that the user will make the right decision. This approach has been shown to be ineffective as it presents the risk information of each app in a "tand-alone" ashion and in a way that requires too much technical knowledge and time to distill useful information.We introduce the notion of risk scoring and risk ranking for Android apps, to improve risk communication for Android apps, and identify three desiderata for an effective risk scoring scheme. We propose to use probabilistic generative models for risk scoring schemes, and identify several such models, ranging from the simple Naive Bayes, to advanced hierarchical mixture models. Experimental results conducted using real-world datasets show that probabilistic general models significantly outperform existing approaches, and that Naive Bayes models give a promising risk scoring approach.

/pdf/using-probabilistic-generative-models-for-ranking-risks-of-4dy5rzsd9y.pdf

Using probabilistic generative models for ranking risks of Android apps

One of Android's main defense mechanisms against malicious apps is a risk communication mechanism which, before a user installs an app, warns the user about the permissions the app requires, trusting that the user will make the right decision. This approach has been shown to be ineffective as it presents the risk information of each app in a "stand-alone" fashion and in a way that requires too much technical knowledge and time to distill useful information. We introduce the notion of risk scoring and risk ranking for Android apps, to improve risk communication for Android apps, and identify three desiderata for an effective risk scoring scheme. We propose to use probabilistic generative models for risk scoring schemes, and identify several such models, ranging from the simple Naive Bayes, to advanced hierarchical mixture models. Experimental results conducted using real-world datasets show that probabilistic general models significantly outperform existing approaches, and that Naive Bayes models give a promising risk scor- ing approach.

Using probabilistic generative models for ranking risks of android apps

Smart electric meters pose a substantial threat to the privacy of individuals in their own homes. Combined with non-intrusive load monitors, smart meter data can reveal precise home appliance usage information. An emerging solution to behavior leakage in smart meter measurement data is the use of battery-based load hiding. In this approach, a battery is used to store and supply power to home devices at strategic times to hide appliance loads from smart meters. A few such battery control algorithms have already been studied in the literature, but none have been evaluated from an adversarial point of view. In this paper, we first consider two well known battery privacy algorithms, Best Effort (BE) and Non-Intrusive Load Leveling (NILL), and demonstrate attacks that recover precise load change information, which can be used to recover appliance behavior information, under both algorithms. We then introduce a stepping approach to battery privacy algorithms that fundamentally differs from previous approaches by maximizing the error between the load demanded by a home and the external load seen by a smart meter. By design, precise load change recovery attacks are impossible. We also propose mutual-information based measurements to evaluate the privacy of different algorithms. We implement and evaluate four novel algorithms using the stepping approach, and show that under the mutual-information metrics they outperform BE and NILL.

http://www.patrickmcdaniel.org/pubs/ccs12b.pdf

Minimizing private data disclosures in the smart grid

Tensor decomposition is a powerful computational tool for multiway data analysis. Many popular tensor decomposition approaches—such as the Tucker decomposition and CANDECOMP/PARAFAC (CP)—amount to multi-linear factorization. They are insufficient to model (i) complex interactions between data entities, (ii) various data types (e.g., missing data and binary data), and (iii) noisy observations and outliers. To address these issues, we propose tensor-variate latent nonparametric Bayesian models for multiway data analysis. We name these models InfTucker. These new models essentially conduct Tucker decomposition in an infinite feature space. Unlike classical tensor decomposition models, our new approaches handle both continuous and binary data in a probabilistic framework. Unlike previous Bayesian models on matrices and tensors, our models are based on latent Gaussian or $t$ processes with nonlinear covariance functions. Moreover, on network data, our models reduce to nonparametric stochastic blockmodels and can be used to discover latent groups and predict missing interactions. To learn the models efficiently from data, we develop a variational inference technique and explore properties of the Kronecker product for computational efficiency. Compared with a classical variational implementation, this technique reduces both time and space complexities by several orders of magnitude. On real multiway and network data, our new models achieved significantly higher prediction accuracy than state-of-art tensor decomposition methods and blockmodels.

Bayesian Nonparametric Models for Multiway Data Analysis

There has been increasing interest in automatic techniques for generating roles for role based access control, a process known as role mining. Most role mining approaches assume the input data is clean, and attempt to optimize the RBAC state. We examine role mining with noisy input data and suggest dividing the problem into two steps: noise removal and candidate role generation. We introduce an approach to use (non-binary) rank reduced matrix factorization to identify noise and experimentally show that it is effective at identifying noise in access control data. User- and permission-attributes can further be used to improve accuracy. Next, we show that our two-step approach is able to find candidate roles that are close to the roles mined from noise-less data. This method performs better than the approach of mining noisy data directly and offering the administrator increased control in the noise removal and candidate role generation phases. We note that our approach is applicable outside role engineering and may be used to identify errors or predict missing values in any access control matrix.

Yuan Qi

Papers

Using probabilistic generative models for ranking risks of Android apps

Using probabilistic generative models for ranking risks of android apps

Minimizing private data disclosures in the smart grid

Bayesian Nonparametric Models for Multiway Data Analysis

Mining roles with noisy data